Test Bank
Introductory Clinical Pharmacology
12th Edition
, Chapter 01, General Principles of Pharmacology
1. After teaching a group of students about the basics of pharmacology, the students
will be able to choose which aspect as the most critical to remember?
A) Drug name
B) Drug class
C) Drug action
D) Drug source
Answer: C
Rationale: Pharmacology is the study of drugs and its action on living organisms.
Thus, an essential aspect of pharmacology is drug action. An understanding of the
drug name, drug class, and drug source is important, but the most critical aspect
related to pharmacology is how the drug acts in the body.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 1
Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Teaching/Learning
Reference: p. 3, Introduction
2. A nurse suspects the client had an adverse reaction to a prescribed medication
due to an interaction with an unreported over-the-counter supplement. Which
action by the nurse will best assist in preventing future similar incidents?
A) File a report with MedWatch
B) File a report with the State Board of Nursing
C) Instruct the client to avoid combining medications in the future
D) Document the incident and report it to the health care provider
Answer: A
Rationale: Nurses play an important role in monitoring for adverse reactions.
Therefore, it is important to submit reports, even if there is uncertainty about the
cause–effect relationship. The FDA protects the identity of those who voluntarily
report adverse reactions.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 9
Cognitive Level: Apply
, Client Needs: Safe and Effective Care Environment: Safety and Infection Control
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 7, Box 1.1 MedWatch and Reporting Adverse Events
3. A nurse is assessing a client and notes the client has developed swelling of the
eyelids and lips after administration of a prescribed medication. What does the
nurse interpret this finding to specifically indicate?
A) Mild allergic reaction
B) Anaphylactic shock
C) Angioedema
D) Drug idiosyncrasy
Answer: C
Rationale: Angioedema is a type of allergic drug reaction manifested by the
collection of fluid in the subcutaneous tissues, most commonly affecting the
eyelids, lips, mouth, and throat. Allergic reactions can be manifested by a wide
range of signs and symptoms such as itching, rashes, and hives. Anaphylactic
shock is a serious allergic reaction that requires immediate medical attention.
Drug idiosyncrasy describes any unusual or abnormal reaction to a drug, one that
is different from the one normally expected.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 5
Cognitive Level: Apply
Client Needs: Physiological Integrity: Reduction of Risk Potential
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 12, Allergic Drug Reactions
4. The nurse is preparing to teach a client about a new drug which is in the fourth
phase of development. Which activity will the nurse explain best illustrates this
phase?
A) Health care providers report adverse effects to FDA.
B) Healthy volunteers are involved in the test.
C) In vitro tests are performed using human cells.
D) The drug is given to clients with the disease.
Answer: A
, Rationale: The postmarketing surveillance phase of drug development
encourages health care professionals to report adverse effects of drugs to the FDA
using MedWatch. Phase 1 of clinical testing involves 20 to 100 healthy volunteers.
In vitro testing of the drug on human or animal cells is done in the pre-FDA phase.
In Phase 2 of clinical testing, the drug is given to clients with the disease for which
the drug is manufactured.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 4
Cognitive Level: Apply
Client Needs: Health Promotion and Maintenance
Integrated Process: Teaching/Learning
Reference: p. 7, Concept Mastery Alert
5. A nurse is assessing a pregnant client who admits to having a cocaine addiction.
Which condition of the baby after birth should the nurse explain and prepare the
client for?
A) Diabetes
B) Hypertension
C) Addiction to drugs
D) CNS defects
Answer: C
Rationale: The nurse informs the client that children born to mothers using
addictive drugs are often born with an addiction to the drug. Children born to
mothers who are addicted to cocaine are not known to be born with diabetes, CNS
defects, or hypertension.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 6
Cognitive Level: Apply
Client Needs: Health Promotion and Maintenance
Integrated Process: Teaching/Learning
Reference: p. 11, Drug Use, Pregnancy, and Lactation
6. A client arrives at the health care clinic and reports taking several pills for a
headache and severe cough without relief. Which adverse effect should the nurse
be aware may develop from this combination?
A) Gastrointestinal bleeding
B) Breathing difficulties
C) Liver damage
D) Anaphylaxis
Introductory Clinical Pharmacology
12th Edition
, Chapter 01, General Principles of Pharmacology
1. After teaching a group of students about the basics of pharmacology, the students
will be able to choose which aspect as the most critical to remember?
A) Drug name
B) Drug class
C) Drug action
D) Drug source
Answer: C
Rationale: Pharmacology is the study of drugs and its action on living organisms.
Thus, an essential aspect of pharmacology is drug action. An understanding of the
drug name, drug class, and drug source is important, but the most critical aspect
related to pharmacology is how the drug acts in the body.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 1
Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Teaching/Learning
Reference: p. 3, Introduction
2. A nurse suspects the client had an adverse reaction to a prescribed medication
due to an interaction with an unreported over-the-counter supplement. Which
action by the nurse will best assist in preventing future similar incidents?
A) File a report with MedWatch
B) File a report with the State Board of Nursing
C) Instruct the client to avoid combining medications in the future
D) Document the incident and report it to the health care provider
Answer: A
Rationale: Nurses play an important role in monitoring for adverse reactions.
Therefore, it is important to submit reports, even if there is uncertainty about the
cause–effect relationship. The FDA protects the identity of those who voluntarily
report adverse reactions.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 9
Cognitive Level: Apply
, Client Needs: Safe and Effective Care Environment: Safety and Infection Control
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 7, Box 1.1 MedWatch and Reporting Adverse Events
3. A nurse is assessing a client and notes the client has developed swelling of the
eyelids and lips after administration of a prescribed medication. What does the
nurse interpret this finding to specifically indicate?
A) Mild allergic reaction
B) Anaphylactic shock
C) Angioedema
D) Drug idiosyncrasy
Answer: C
Rationale: Angioedema is a type of allergic drug reaction manifested by the
collection of fluid in the subcutaneous tissues, most commonly affecting the
eyelids, lips, mouth, and throat. Allergic reactions can be manifested by a wide
range of signs and symptoms such as itching, rashes, and hives. Anaphylactic
shock is a serious allergic reaction that requires immediate medical attention.
Drug idiosyncrasy describes any unusual or abnormal reaction to a drug, one that
is different from the one normally expected.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 5
Cognitive Level: Apply
Client Needs: Physiological Integrity: Reduction of Risk Potential
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 12, Allergic Drug Reactions
4. The nurse is preparing to teach a client about a new drug which is in the fourth
phase of development. Which activity will the nurse explain best illustrates this
phase?
A) Health care providers report adverse effects to FDA.
B) Healthy volunteers are involved in the test.
C) In vitro tests are performed using human cells.
D) The drug is given to clients with the disease.
Answer: A
, Rationale: The postmarketing surveillance phase of drug development
encourages health care professionals to report adverse effects of drugs to the FDA
using MedWatch. Phase 1 of clinical testing involves 20 to 100 healthy volunteers.
In vitro testing of the drug on human or animal cells is done in the pre-FDA phase.
In Phase 2 of clinical testing, the drug is given to clients with the disease for which
the drug is manufactured.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 4
Cognitive Level: Apply
Client Needs: Health Promotion and Maintenance
Integrated Process: Teaching/Learning
Reference: p. 7, Concept Mastery Alert
5. A nurse is assessing a pregnant client who admits to having a cocaine addiction.
Which condition of the baby after birth should the nurse explain and prepare the
client for?
A) Diabetes
B) Hypertension
C) Addiction to drugs
D) CNS defects
Answer: C
Rationale: The nurse informs the client that children born to mothers using
addictive drugs are often born with an addiction to the drug. Children born to
mothers who are addicted to cocaine are not known to be born with diabetes, CNS
defects, or hypertension.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 6
Cognitive Level: Apply
Client Needs: Health Promotion and Maintenance
Integrated Process: Teaching/Learning
Reference: p. 11, Drug Use, Pregnancy, and Lactation
6. A client arrives at the health care clinic and reports taking several pills for a
headache and severe cough without relief. Which adverse effect should the nurse
be aware may develop from this combination?
A) Gastrointestinal bleeding
B) Breathing difficulties
C) Liver damage
D) Anaphylaxis
