Summary Liver Function Tests Study Notes
Important List less common secondary (possibly modifiable) causes of hyperlipidaemia: nephrotic syndrome, drugs (thiazides, oestrogens, glucocorticoids), cholestatic jaundice. Understand other acute phase reactants: fibrinogen, prothrombin, haptoglobin, factor VIII, platelets, lipoprotein a, complement, caeruloplasmin FUNCTIONS OF THE LIVER 1.Digestive Production of bile to aid in digestion and absorption of fats and fat soluble vitamins 2.Metabolic A most important organ in the metabolism of proteins, carbohydrates and fats. 3.Storage Vitamin B12 sufficient stores for 1 – 3 years Vitamin A sufficient stores for 10 months Vitamin D sufficient stores for 3 – 4 months* Vitamin K stored in small amounts Folic acid stored in small amounts Ferritin apoferritin in hepatocytes binds with any excess iron to form ferritin. Iron is released from ferritin as required. *children who live in cold climates and who remain indoors throughout the winter, may develop rickets in the springtime, as the stores of Vitamin D acquired during preceding summer have become exhausted. 4.Detoxification / excretion of drugs and other substance
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