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NUR 265 Exam 1 Study Guide: Latest Updated: Guaranteed A+

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 Nephrotic Syndrome: o NS is a condition of increased glomerular permeability that allows larger molecules to pass through the membrane into the urine and then be excreted. o This causes massive loss of protein in the urine, edema formation, and decreased plasma albumin levels.  Most common cause is an immune or inflammatory response.  Genetic defects- Fabry disease.  Altered liver production occurs with NS which results in increased lipid production, and hyperlipidemia.  Proteinuria- severe protein loss more than 3.5 g in 24- hour urine sample. o Key features:  Massive proteinuria  Hypoalbuminemia  Edema (facial and periorbital)  Lipiduria  Hyperlipidemia  Increased coagulation  Reduced kidney function o Treatment- immunosu


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