CPJE Top 500 Drugs & Doses Exam With 100% Correct Answers 2024

CPJE Top 500 Drugs & Doses Exam With 100% Correct Answers 2024 Acetazolamide - answerDiamox MOA- Carbonic Anhydrase Inhibitor sun protection and hydration are recommended - for Altitude sickness and motion sickness --> 125 mg BID - CI: sulfa allergy Sevelamer - answer- Renvela (carbonate) or Renagel (HCl) - CI: Bowel obstruction - Indication: hyperphosphatemia in CKD - non-Ca, Non-Al based phosphate binder - lower TC and LDL by 15%-30% - Sevelamer carbonate maintains Bicarbonate concentrations - SE: NVD (>20%) - 800- 1,600 mg TID w/ meals Calcitrol (Rocaltrol)- Cap, Sol'n, Injection Calcifediol (Rayaldee ER) - answer- Vitamin D analogs - increase intestinal absorption of Ca and provide a negative feedback to parathyroid gland - CI: hypercalcemia, vitamin D toxicity - Indication: Dialysis, Vitamin D deficiency and secondary hyperparathyroidism in CKD - Dose for Calcitriol ------ CKD: 0.25-0.5 mcg PO daily ------Dialysis: 0.5-1 mcg PO daily of 0.5-4 mcg IV 3X weekly Vitamin D - answerVitamin D3--> Rocaltrol calcitriol Vitamin D2--> Drisdol ergocalciferol Cinacalcet - answerSensipar Dialysis: 30-180 mg PO QD w/ food CI: Hypocalcemia MOA: calcimimetic --> lowers PTH, Ca, PO4 SE: hypocalcemia Penicillin - answerPen VK - take on empty stomach - tablet, suspension Penicillin G Benzathine - answerBicillin L-A BBW: not for IV use --> can cause cardiorespiratory arrest and death Indication: Syphillis Amoxicillin - answerAmoxil, Moxatag - Tablet, Capsule, Chewable, suspension Amoxicillin + Clavulanate - answerAugmentin - CI: hx of cholestatic jaundice or hepatic dysfunction assosicated w/ previous use, Severe renal Impairment CrCl <30 mL/min - Tablet, chewable, suspension Cephalexin - answerKeflex (PO) 1st generation: Skin infections MSSA, strep throat Cefuroxime - answerCeftin, Zinacef ----2nd generation Common uses: otitis media, CAP, Sinus Infection *** in sulfa allergy in children--> Ceftin is acceptable alternative for otitis media Cefotetan (Cefotan) and cefoxitin - answeranaerobe coverage (B. fragilis) ****Cefotetan can cause disulfiram like reaction w/ alcohol ingestion ----- 1-2 g IV/IM Q12H recommended antibiotics for prophylaxis before colorectal surgeries Ceftriaxone - answerRocephin 3rd generation no renal adjustment once daily dosing - do not use in neonates (0-28 days) - Common uses: CAP, meningitis, SBP, Pyelonephritis *** Cefotaxime is another 3rd generation cephalosporin Ceftaroline - answerTeflaro (5th gen cephalosporin) **** The only B-lactam that is active against MRSA Cefazolin (IV) - answerAncef, Kefzol - 1st generation ceph - surgical prophylaxis Ertapenem - answerInvanz - it is dosed once daily IV/IM - Stable in NS only common uses: ESBL-producing bacteria, DFI **** No pseudomonas, acinetobacter or enterococcus Fluoroquinolones - answerBBW: CNS effects (Seizures hx), Tendonitis, peripheral neuropathy - may exacerbate muscle weakness related to myasthenia gravis **** may use if no other alternative available for uncomplicated UTI, bacterial sinusitis, chronic bronchitis ***Moxifloxcin --> do not use in UTI, highest risk for QT prolongation Ciprofloxacin - answerCipro, Ciloxin eye drops, ciprodex ear drops (+dexamethasone), Otovel ear drops ( + fluocinolone) Cetraxal sol'n--- Ciprofloxacin for acute