MMSC 491 EXAM 2 /WELL STRUCTURED QUESTIONS AND CORRECT ANSWERS 2024/2025 GRADED A+.

1. The term phenotype can be applied to a wide range of maifestations.Whichof the following protperties, if any do not constitute a phenotypic manifesta-tion: The sequance of a persons beta globin gene 2. Which, if any, of the following is incorrect? when used in human genetic: - Incorrect:The term dominant and recessive apply equally to allels and phenotypes Correct: - Dominant describes a phenotype that is manifestated in the heterozygotem thatis, the phenotype is attributed to just a single allele -Recessive describes a phenotype that is manifest as a result of the combinedeffects of boht alleles at a locus -The AB blood group is an example of a co-dominant phenotype 3. With respectto autosomal recessive inheritance,which,if any, of the follow-ing statements is incorrect: Incorrect: Heterozygotes are always asymptomatic carriers Correct: -Affected individuals normally have unaffected parents -for unaffected parents who have previously affected child, there is a 1 in 4 risk ofhaving an affected child on each occasion that they produce a new child -Some affected individuals have alleles with idnetical pathogenic mutations but manyhave two different mutant alleles and are described as compund heterozygotes 4. With respect to X-chromsome inactivation in females, which, if any of thefollowing statements is incorrect: Incorrect:The process involves epeigentic si-lencing of each gene on one of 3 / 5 the two x chromsomes, either the maternal X chromsome or the paternal X chromsome Correct -X inactiavation first occurs in the preimplantation female mammalian embryo -One of the two X chromsomes in each diploid cell of a normal women is randomlyselected to undergo X-inactation and becomes highly condensed -Once the decision is made to inactavate a paternal X or the maternal X in a cell, alldescendant cells will continue with that pattern of X-inactivation 5. Wth respect to X-linked recessive inheritance, which, if any of the followingstatements is false: False:Women are always asymptomatic True -Males with just one mutant allele are affected because, lacking a second X-chrom-some, they do not have a normal allele