FUNDAMENTAL’S OF CHEMOTHERAPY IMMUNOTHERAPY ADMINISTRATION EXAM QUESTIONS AND VERIFIED SOLUTIONS 2024/2025 GRADED A+.

1. neoadjuvant therapy: when chemotherapy is used before a primary treatment toreduce the size of a solid tumor 2. adjuvant therapy: Chemotherapy used after the primary treatments (often usedin solid tumor cancers 3. Leukemia treatment: A hematologic malignancy often treated in phases thatinvolves chemotherapy 4. Induction: the initial phase of chemotherapy usually initiated in the hospital because of it's potential for side effects and complications from the severe myelo-suppression 5. Consolidation phase: once the induction phase is completed. Done to ensure the tx takes effect and decreases the chance of recurrence. This tx is vital b/c leukemia cells are almost always still present to a small degree in the bone marroweven if not clinically apparent 6. Reinduction therapy: Used when a patient experiences a recurrence of malig-nancy months later after a patient has successfully responded to induction and consolidation. 7. Myeloablation: When bone marrow is purposely obliterated through chemother- apy or radiation to prepare for blood stem cell transpland or bone marrow transplant. Used to tx. blood malignancies (leukemia/lymphoma) 8. Treatment strategies for chemo: Chemo can be used alone or with other formsof tx. In conjunction with surgery or radiation In combination with immunotherapy drugs or different types of chemo drugs 9. complete response: no cancer identified for at least one month 10. partial response: measurable tumor is reduced by 50% for at least 1 monthwithout development of new tumors 11. stable dz: tumorisreduced in side by lessthan 50% orlessthan a 25% increasein tumor growth occurs 12. Progressive dz: tumor growth of more than 25% or development of new cancergrowth in the body 13. relapse/recurrence: new tumor growth after experiencing a complete response 14. S phase chemo tx: prevent cells from making DNA/RNA by inhibiting thebiosynthesis of nucleic acids Antifolates (methotrexate)