Chronic Obstructive Pulmonary Disease (Exam #3) Questions & Answers 2024
Chronic Obstructive Pulmonary Disease (Exam #3) Questions & Answers 2024 COPD Definition - ANSWER-- the presence of airflow obstruction that is attributable to either chronic bronchitis and/or emphysema. Who gets COPD and what is an obstructive - ANSWER-- Mostly smokers get this - Obstructive: A narrowing & limits air flow in & out of the lungs - Stiff lungs expand a lot of energy breathing out Chronic bronchitis: - ANSWER-- the presence of a productive cough most days during 3 consecutive months in each of 2 successive years Emphysema: - ANSWER-- abnormal permanent enlargement of the alveoli and is accompanied by destruction of the lung alveoli without obvious fibrosis. - They do lung biopsy in order to see this Pathophysiology: Emphysema - COPD - ANSWER-- Exposure to ROS & nicotine increases alveolar injury & protease activity, while at the same time decreases antiproteases - Overactive protease & inhibit antiproteases Pathophysiology: Emphysema - Steps of COPD (Picture) - ANSWER-1. Tobacco 2. ROS (Free radicals) 3. Inactivation of antiproteases 4. Increases neutrophil elastase - A lot of destruction & not a lot of replacement in the alveolar
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