ONS FUNDAMENTALS (ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY) TUDY GUIDE EXAM 2024

ONS FUNDAMENTALS (ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY) TUDY GUIDE EXAM 2024 when chemo is used before primary treatment (surgery) to reduce the size of a tumor - CORRECT ANSWER-neoadjuvant therapy neoadjuvant therapy is common for what 2 kind of cancers? - CORRECT ANSWERcolon and breast when chemo is used after primary (surgery, radiation) - CORRECT ANSWER-adjuvant induction - CORRECT ANSWER-start of chemo consolidation - CORRECT ANSWER-testing labs and such after chemo myeloblation - CORRECT ANSWER-destroying the bone marrow in order to a transplant for leukemias what do alkylayting agents do? - CORRECT ANSWER-directly damage the DNA to stop replication Alkylating agents major side effects - CORRECT ANSWER-naseau and vomititng, myelosupression, neurotoxicity alkylating ages examples - CORRECT ANSWER-cisplatin, carboplatin, busulfan, cyclophosphamide, ifosfamide, melphalan, oxaliplatin cyclophosphamide - CORRECT ANSWER-used for leukemias, lymphomas, myeloma, breast and ovarian cancer, neuroblastoma, and retinoblastoma. HYDRATE before and after (can cause acute hemmoragic cystitis). can cause liver and renal damage. can cause extreme nausea, and cardiac issues. contraindicated if extreme marrow suppression. cisplatin - CORRECT ANSWER-used for bladder, testes, ovaries, endometrial cancer, lung cancer, head and neck and squamous cell. contraindicated for bad kidneys, hearing loss, neuropathy, lactation, and myelosupresion. vesicant. can cause neuropathy and ototoxicmy, extreme nausea, delayed nausea. need fluids! carboplatin - CORRECT ANSWER-ovaries, head and neck, lung, cervial, metastatic breast, testicular, lymphoma, relapse leukemia. contraindicated with marrow suppression, lactation, and bleeding tendencies. anaphylactic reactions can occur!