UNE Biochem 1005 Unit 2 exam questions & answers 2024

UNE Biochem 1005 Unit 2 exam questions & answers 2024 1. Pyruvate dehydrogenase kinase catalyzes a reaction that results in which of the following? - ANSWER-The phosphorylation and inactivation of E1 subunit (pyruvate dehydrogenase complex 1. Which of the following intermediates is an allosteric activator of pyruvate kinase? - ANSWER-a. Fructose 1.6 bisphosphate 1. Which of the following is the initial second messenger in the signaling cascade initiated by glucagon? - ANSWER-a. cAMP 1. Hereditary fructose intolerance in caused by a deficiency in aldolase B. These individuals may present with hypoglycemia due to an accumulation of fructose 1-P in the cell and inhibition of which of the following pathways? - ANSWER-a. Gluconeogenesis and glycogenolysis 1. Following insulin binding its receptor and autophosphorylation of the beta chain, what is the initial step in the cascade of events? - ANSWER-a. Recruitment of the insulin receptor substrate 1. What sequence of enzymes allows for the synthesis of glycogen from glucose 6-P? - ANSWER-Phosphoglucomutase, UDP-glucose phosphorylase, glycogen synthase amylo-(1,4a1,6)-transglycosylase 1. Complex II, succinate dehydrogenase, is not considered to be part of the process of oxidative phosphorylation because it is unable to do which of the following activities? - ANSWER-a. Pump protons from the mitochondrial matrix to the intermembrane space 1. Which of the following is the primary GLUT transporter in skeletal muscle and adipose tissue? - ANSWER-GLUT 4 1. Which of the following best describes the net effect of the 8 steps of the TCA cycle? - ANSWER-a. This process completely oxidizes an acetyl group to carbon dioxide