UST ABSN Pathopharmacology 1 (100% Accurate answers)

A drug is any chemical that can affect living processes correct answers How do you define the word drug? Pharmacology can be defined as the study of drugs and their interaction with living things correct answers Define pharmacology study of effect of drugs in man (as compared to animals or comparative pharmacology correct answers Define clinical pharmacology also known as therapeutics, pharmacotherapeutics emphasizes the disease state and its characteristics including therapy for and use of drugs in prevention and treatment of condition correct answers what are pharmacotherapeutics? Drugs used to destroy or eliminate pathogenic cells or organisms. The term is usually restricted to anti-infectives and cancer chemotherapy. correct answers what are chemotherapeutic agents? Toxicology deals with the effects of drugs. Toxicity is measured through the Therapeutic Index. correct answers what is toxicology and how do we measure a drugs toxicity? therapeutic index is a ratio that measures toxicity. The ratio is found by putting the dose *capable of killing 50% of animals (LD50) over than required to acheive a beneficial effect in 50% of animals (ED50). In clinical practice the THERAPEUTIC INDEX is described as the ratio of the dose that causes toxicity over the dose that provides therapeutic effect. correct answers What is the therapeutic index? Tolerance is the hyporeactivity that occurring from chronic exposure to a drug. Achievement of the same effects of the drug requires larger and larger doses. correct answers what is tolerance? Cross tolerance may happen when tolerance occurs across drugs of the same class or across drugs that have the same pharmacological effects correct answers What is cross tolerance and how does it occur? Tolerance to opioids, barbiturates, and alcohol correct answers what are some examples of neurological adaptation/ cellular tolerance to drugs? metabolic drug tolerance occurs when the body has an increased rate of elimination of the drug. correct answers What is metabolic drug tolerance? enzyme induction which occurs when there is an increased activity of enzymes (the drug transport system) correct answers what is the most common form of metabolic tolerance?