CPHON PRACTICE TEST WITH COMPLETE SOLUTION

Examples of Alkylating Agents - ANSWER Carboplatin, Cisplatin, Carmustine, Lomustine, Cytoxan, Ifosfamide, Melphalan, Temozolomide, Thiotepa Examples of Antimetabolites (Cell-cycle Specific) - ANSWER MTX, 5-FU, ARA-C, 6-MP, 6-TG Examples of Plant Detrivatives (Cell-cycle Specific) - ANSWER Etoposide, irinotecan, vincristine Examples of Antibiotics for Cancer treatment - ANSWER Dactinomycin, Bleomycin Examples of Anthracyclines - ANSWER Doxorubicin, Daunorubicin Misc chemotherapy class examples - ANSWER Peg, procarbazine, decarbazine If Extravasation, apply cold compresses for every chemo except - ANSWER Vincristine and Etoposide. Apply warm compress for these chemos Common late effect of Alkylating Agents - ANSWER Thyroid Abnormalities. Examples: Cytoxan, Melphalan, Ifos, and Busulfan Common late effect of anthracyclines - ANSWER Cardiac Toxicity. Examples: Doxo, Dauno, and Mitoxantrone Common late effect of vinca alkaloids - ANSWER Peripheral Neuropathy. Examples: Vincristine, Vinblastine, Etop Common late effect of heavy metal agents - ANSWER Hearing Deficits. Examples: Cisplatin and Carboplatin Common late effect of Hormone Agents - ANSWER Cataracts, Glaucoma, Uveitis: Prednisone and Dexamethasone Common Cancers with Late Thyroid Issues - ANSWER Hodgekins, Germ Cell, CNS tumors, NBL treated with radiolabeled Ab, BMT with TBI Common Cancers with Late GU Issues - ANSWER NBL, Wilm's, Fanconis Common Cancers with Late Reproductive Issues - ANSWER Medulloblastoma, Osteosarcoma, Ewing