Drugs for Central Nervous System Problems Visovsky: Introduction to Clinical Pharmacology, 10th Edition Exam 100% solved

Drugs for Central Nervous System Problems Visovsky: Introduction to Clinical Pharmacology, 10th Edition Exam 100% solved 1. Which neurotransmitter has an inhibitory action within the CNS? a. Epinephrine b. Acetylcholine c. Norepinephrine d. Gamma-aminobutyric acid - answerd. Gamma-aminobutyric acid 2. A 73-year-old male patient newly diagnosed with Parkinson's disease (PD) is prescribed a dopamine agonist. The patient's wife asks you to explain how this class of drugs will work to help her husband. What is your best response? a. "Dopamine agonists reduce levels of acetylcholine to restore gait and balance." b. "Dopamine agonists use an enzyme to break down dopamine to improve PD symptoms." c. "Dopamine agonists prevent the buildup of beta amyloid plaques to improve coordination." d. "Dopamine agonists reduce muscle rigidity and tremors by increasing dopamine levels." - answerd. "Dopamine agonists reduce muscle rigidity and tremors by increasing dopamine levels." 3. A patient placed on the drug tolcapone (Tasmar) for the relief of symptoms of Parkinson's disease asks you how this drug works for the disease. What is your best response? a. "Tolcapone acts as a dopamine agonist, replacing the activity of dopamine." b. "Tolcapone forces the substantia nigra to increase production of natural dopamine." c. "Tolcapone suppresses the enzyme that breaks down naturally occurring dopamine." d. "Tolcapone increases the number of dopamine receptors sites." - answerc. "Tolcapone suppresses the enzyme that breaks down naturally occurring dopamine." 4. Why are carbidopa and levodopa usually given together? a. Carbidopa is a dopamine agonist and levodopa is a dopamine antagonist. b. Levodopa is a dopamine agonist and carbidopa is a dopamine antagonist. c. Carbidopa enhances the action of levodopa, and less drug is needed. d. Levodopa reverses or prevents the side effects of carbidopa. - answerc. Carbidopa enhances the action of levodopa, and less drug is