Med Biochem Test 3 Exam With Accurate Solution 2023 A+

Med Biochem Test 3 Exam With Accurate Solution 2023 A+ 1. Why do we degrade proteins? - Answer-Protein function & Nutrition 2. What can affect protein function? - Answer-Misfolded, Deactivated, turning on/off a signal pathway 3. How does degrading proteins help nutrition? - Answer-Access to essential amino acids, Energy 4. Why do we degrade Amino Acids? - Answer-We cannot store amino acids, and to break them down into other molecules including vitamins 5. What are some disease states that come from a deficiency in protein degradation? - Answer- Neurodegenerative and myodegenerative disorders, Cardiac protein homeostasis 6. What is a drug target for future drugs to target degradation pathways? - Answer-Proteasome inhibitors 7. What drug is an approved proteasome inhibitor that is used to treat multiple myeloma? - Answer-Bortezomib 8. How are proteins broken down in the stomach and SI? - Answer-Broken down by pepsin 9. How are proteins broken down in the Lysosome? - Answer-Protein is proteolyzed by lysosomal enzymes 10. How are proteins degraded by the proteasome? - Answer- Continues...