OCN exam
alkylating agents - answer Cisplatin, Carboplatin, Oxaliplatin, ifosfamide,
cyclophosfamide
Alkylating Agents - answer Common ADEs include myelosuppression, nausea
vomitting, GU toxicities
Oxaliplatin - answer Cold dysesthesia is common, can cause neuropathy,
Ifosfamide - answer must be given with mesna. Can cause hemorrhagic cystitis and
CNS toxicities
Antimetabolites - answer Drugs such as cytarabine, methotrexate, florouracil (5fu)
Cytarabine - answer Requires neuro assessment before each dose if HD, ADEs
include myelosuppression, n/v, keratitis
5FU - answer Can cause stomatitis, stomach ulcers, teach good oral care
Antitumor Antibiotics - answer Can cause cardiopulmonary toxicities with cumulative
doses, severe myelosupression
Antitumor antibiotics - answer drugs such as Daunorubicin, Doxorubicin, Idarubicin,
bleomycin (most are vesicants)
Plant Alkaloids - answer Can cause peripheral and sensory neuropathies, general
myleosuppression, can cause hypersensitivity
Alkaloids - answer include drugs like vincristine and paclitaxel, docetaxel
Vincristine - answer Vesicant! Fatal if given intrathecal! given on y gravity tubing
alkylating agents - answer Cisplatin, Carboplatin, Oxaliplatin, ifosfamide,
cyclophosfamide
Alkylating Agents - answer Common ADEs include myelosuppression, nausea
vomitting, GU toxicities
Oxaliplatin - answer Cold dysesthesia is common, can cause neuropathy,
Ifosfamide - answer must be given with mesna. Can cause hemorrhagic cystitis and
CNS toxicities
Antimetabolites - answer Drugs such as cytarabine, methotrexate, florouracil (5fu)
Cytarabine - answer Requires neuro assessment before each dose if HD, ADEs
include myelosuppression, n/v, keratitis
5FU - answer Can cause stomatitis, stomach ulcers, teach good oral care
Antitumor Antibiotics - answer Can cause cardiopulmonary toxicities with cumulative
doses, severe myelosupression
Antitumor antibiotics - answer drugs such as Daunorubicin, Doxorubicin, Idarubicin,
bleomycin (most are vesicants)
Plant Alkaloids - answer Can cause peripheral and sensory neuropathies, general
myleosuppression, can cause hypersensitivity
Alkaloids - answer include drugs like vincristine and paclitaxel, docetaxel
Vincristine - answer Vesicant! Fatal if given intrathecal! given on y gravity tubing
