NURS 660 (Questions with error-free answers)

Typical antipsychotics correct answers What class of antipsychotic are these Neuroleptics, Conventional, First Generation, Dopamine Receptor Antagonists? Atypical Antipsychotics correct answers What class of antipsychotic are these Second Generation, Serotonin-Dopamine Receptor Antagonists Dopamine D2 receptor correct answers This receptor has the benefit of reducing positive symptoms. Possible side effects include: Parkinsonism, akathisia, tardive dyskinesia, endocrine effects such as prolactin secretion, menstrual changes and sexual dysfunction. Serotonin 5-H2a receptor correct answers This receptor has the benefit of reducing EPS Possible side effects: Sexual dysfunction Serotonin 5HT2c receptor correct answers The benefit of this receptor is unknown Side effect is weight gain Histamine H-1 receptor correct answers The benefit of this receptor is sedation Side effects are sedation, increased appetite, weight gain and hypotension Muscarinic cholinergic receptors correct answers The benefit of the receptor is that it reduces EPS Side effects are autonomic changes such as blurry vision, dry mouth, constipation, urinary retention, tachycardia and memory dysfunction. a1-adrenergic receptors correct answers Benefit of receptor unknown Side effects are orthostatic hypertension, dizziness and reflex tachycardia. a2-adrenergic receptors correct answers Benefit of receptor unknown Side effects are drug interactions D2-Agonist actions? correct answers What makes an antipsychotic conventional? D2 antagonist/First generation antipsychotics/Conventional antipsychotics/Typical antipsychotics correct answers These antipsychotics share the primary pharmacological property of D2 antagonism, which is responsible not only for their antipsychotic efficacy, but also for many of their side effects. Conventional Antipsychotic correct answers These drugs have pharmacological properties in addition to D2 antagonism, they block muscarinic cholinergic receptors, histamine h-1 receptors and/or a1-adrenergic receptors. 60-80% correct answers Antipsychotic properties happen when how much of the D2 receptor is blocked?