UNE Medical Biochemistry Midterm Review Questions & Answers Rated 100% Correct!!

UNE Medical Biochemistry Midterm Review Questions & Answers Rated 100% Correct!! Ribose and NADPH A family presents for genetic counseling. The couple has two female children who are alive and well; however, their infant son recently died in the nursery with severe hemolysis (lysis of red blood cells) and jaundice. The wife recalls she lost a brother in infancy with severe hemolysis, induced after a viral infection. The physician suspects a glucose-6-phosphate dehydrogenase deficiency, this would result in a deficiency in which of the following compounds in red blood cells? Transketolase A patient presents to the emergency department with lactic acidosis. A deficiency in thiamine (TPP) is suspected and this will be consistent with a decrease in the activity of following enzymes? UDP-Glucose Galactose 1-phosphate is initially converted to glucose 1-phosphate and requires which of the following compounds? Thiamine diphosphate Which of the following cofactors is required for transketolase activity? Glyceraldehyde 3-phosphate Aldolase B facilities a reaction that cleaves fructose 1-phosphate into two 3-carbon molecules that will enter glycolysis as which of the following compounds? Glycolysis High levels of activity of the non-oxidative portion of the pentose phosphate pathway will directly produce intermediates of which of the following pathways? Glucose 6-phosphate dehydrogenase The major regulatory step of the pentose phosphate pathway is catalyzed by which enzyme? VLDL particles