BMTCN Exam questions well answered rated A+ 2023/2024

BMTCN Examanthracycline: examples & side effects - correct answer -doxorubicin, idarubicin, daunorubicin, mitoxantrone -associated with cardiac issues (CHF, cardiomyopathy, arrhythmias) foscarnet: indication + administration + key side effect - correct answer -antiviral (i.e. CMV treatment) -pre-hydration essential d/t potential for renal tubule effects -can cause low levels of any/all electrolytes (and hyperphosphatemia) Live vaccines - correct answer MMR and varicella/shingles (wait at least 24 months post-transplant) Reticulocyte - correct answer immature red blood cell mast cell - correct answer myeloid cells that release chemicals (such as histamine) that promote inflammation. monoblast - correct answer myeloid cell that can give rise to macrophages, monocytes, and dendritic cells myeloblast - correct answer myeloid cell that can give rise to neutrophils, eosinophils, and basophils NK cell - correct answer lymphoid cell responsible for suppressing viruses and destroying tumor cells spleen - correct answer -immune system organ that filters WBCs, platelets, and other substances -reservoir for ~1/3 total platelet volume -removed unused platelets from circulation in ~10 days thymus gland - correct answer immune system organ that forms T cells sibling match probability - correct answer 25% auto transplant diseases - correct answer Hodgkin's disease, N-H Lymphoma, MM, & solid tumors drugs given to donor for PB stem cell harvest - correct answer G-CSF & plerixafor HLA chromosome - correct answer chromosome 6 FACTS guideline: infectious disease testing within ___________ days of collection - correct answer 30 days minimum age for peripheral blood bone marrow harvest & max pediatric blood processing amount (ml/kg) & max adult blood processing volume - correct answer -13 years old (most centers) -200-250 ml/kg -12-15L (2-3xs total body blood volume) most common stem cell collection method: adult vs pediatric (%?) - correct answer -adult: peripheral blood stem cells (~88%) -pediatric: bone marrow (76-81%) G-CSF -drug name & class -usage -dose/route -administration timing -side effects (common) - correct answer -filgrastim, glycoprotein -used for stem cell mobilization -10 mcg/kg/day SC (up to 32mcg) -starts 4-5 days prior to and until last session of stem cell collection