NR 503 Midterm Exam
Question 1
Which of the following statements best describe efficacy?
• It is an estimate of the benefit of treatment under ideal conditions
• It is an estimate of the reduction of disease in treated groups
Question 2
A study is conducted for a pharmaceutical agent that has shown promise for reducing heart disease
among women. In order to more fully test the agent, an additional study is done restricting the
participants to be r&omized to those who have a history of hypertension. Which of the following
advantages cannot be claimed by the researchers?
• The generalizability of the study is increased
Question 3
What is the main advantage of the r&omization of the 168 study participants to one of the two drug
treatment groups?
• Reduces the potential for selection bias in allocation of treatment group
Question 4
After entry into the study, patients were first classified into three groups, those who had a previous
AMI, those with a first AMI who were at high risk for other cardiovascular diseases such as congestive
heart failure, & those with a first AMI who were at low risk for other cardiovascular diseases. Which
term best describes the study design?
• R&omized clinical trial with stratified r&omization
Question 5
After assignment to treatment group, 77% of those in the placebo group were men, while 80% of
those in the drug X group were men. Which statement is most likely to be true?
Question 1
Which of the following statements best describe efficacy?
• It is an estimate of the benefit of treatment under ideal conditions
• It is an estimate of the reduction of disease in treated groups
Question 2
A study is conducted for a pharmaceutical agent that has shown promise for reducing heart disease
among women. In order to more fully test the agent, an additional study is done restricting the
participants to be r&omized to those who have a history of hypertension. Which of the following
advantages cannot be claimed by the researchers?
• The generalizability of the study is increased
Question 3
What is the main advantage of the r&omization of the 168 study participants to one of the two drug
treatment groups?
• Reduces the potential for selection bias in allocation of treatment group
Question 4
After entry into the study, patients were first classified into three groups, those who had a previous
AMI, those with a first AMI who were at high risk for other cardiovascular diseases such as congestive
heart failure, & those with a first AMI who were at low risk for other cardiovascular diseases. Which
term best describes the study design?
• R&omized clinical trial with stratified r&omization
Question 5
After assignment to treatment group, 77% of those in the placebo group were men, while 80% of
those in the drug X group were men. Which statement is most likely to be true?
