11/16/23, 2:42 PM Chapter 12- Midterm 2 (Campbell)
Campbell Biology, Cdn. Ed., 2e (Reece et al.)
Chapter 12 The Cell Cycle
1) The centromere is a region in which
A) chromatids remain attached to one another until anaphase.
B) metaphase chromosomes become aligned at the metaphase plate.
C) chromosomes are grouped during telophase.
D) the nucleus is located prior to mitosis.
E) new spindle microtubules form at either end.
Answer: A
Type: MC
Topic: Concept 12.1
Skill: Knowledge/Comprehension
2) Starting with a fertilized egg (zygote), a series of five cell divisions would produce an early
embryo with how many cells?
A) 4
B) 8
C) 16
D) 32
E) 64
Answer: D
Type: MC
Topic: Concept 12.1
Skill: Application/Analysis
3) If there are 20 chromatids in a cell, how many centromeres are there?
A) 10
B) 20
C) 30
D) 40
E) 80
Answer: A
Type: MC
Topic: Concept 12.1
Skill: Application/Analysis
1
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,11/16/23, 2:42 PM Chapter 12- Midterm 2 (Campbell)
4) For a newly evolving protist, what would be the advantage of using eukaryote-like cell
division rather than prokaryotic binary fission?
A) Binary fission would not allow for the formation of new organisms.
B) Cell division would allow for the orderly and efficient segregation of multiple linear
chromosomes.
C) Cell division would be faster than binary fission.
D) Cell division allows for lower rates of error per chromosome replication.
E) Binary fission would not allow the organism to have complex cells.
Answer: B
Type: MC
Topic: Concept 12.1
Skill: Synthesis/Evaluation
5) Suppose a biologist can separate one of a dozen pieces of chromatin from a eukaryotic
(animal) nucleus. It might consist of which of the following?
A) one-twelfth of the genes of the organism
B) two chromosomes, each with six chromatids
C) a single circular piece of DNA
D) two long strands of DNA plus proteins
E) two chromatids attached together at a centromere
Answer: D
Type: MC
Topic: Concept 12.1
Skill: Knowledge/Comprehension
6) At which phase are centrioles beginning to move apart in animal cells?
A) telophase
B) anaphase
C) prometaphase
D) metaphase
E) prophase
Answer: E
Type: MC
Topic: Concept 12.2
Skill: Knowledge/Comprehension
7) If cells in the process of dividing are subjected to colchicine, a drug that interferes with the
formation of the spindle apparatus, at which stage will mitosis be arrested?
A) anaphase
B) prophase
C) telophase
D) metaphase
E) interphase
Answer: D
Type: MC
Topic: Concept 12.2
Skill: Application/Analysis
2
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,11/16/23, 2:42 PM Chapter 12- Midterm 2 (Campbell)
8) If there are 20 centromeres in a cell at anaphase, how many chromosomes are there in each
daughter cell following cytokinesis?
A) 10
B) 20
C) 30
D) 40
E) 80
Answer: A
Type: MC
Topic: Concept 12.2
Skill: Application/Analysis
9) Where do the microtubules of the spindle originate during mitosis in both plant and animal
cells?
A) centromere
B) centrosome
C) centriole
D) chromatid
E) kinetochore
Answer: B
Type: MC
Topic: Concept 12.2
Skill: Knowledge/Comprehension
10) Taxol is an anticancer drug extracted from the Pacific yew tree. In animal cells, Taxol
disrupts microtubule formation by binding to microtubules and accelerating their assembly from
the protein precursor, tubulin. Surprisingly, this stops mitosis. Specifically, Taxol must affect
A) the formation of the mitotic spindle.
B) anaphase.
C) formation of the centrioles.
D) chromatid assembly.
E) the S phase of the cell cycle.
Answer: A
Type: MC
Topic: Concept 12.2
Skill: Application/Analysis
3
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, 11/16/23, 2:42 PM Chapter 12- Midterm 2 (Campbell)
11) Which of the following are primarily responsible for cytokinesis in plant cells but not in
animal cells?
A) kinetochores
B) Golgi-derived vesicles
C) actin and myosin
D) centrioles and centromeres
E) cyclin-dependent kinases
Answer: B
Type: MC
Topic: Concept 12.2
Skill: Knowledge/Comprehension
12) In which group of eukaryotic organisms does the nuclear envelope remain intact during
mitosis?
A) seedless plants
B) dinoflagellates
C) diatoms
D) dinoflagellates and diatoms only
E) seedless plants, dinoflagellates, and diatoms
Answer: D
Type: MC
Topic: Concept 12.2
Skill: Knowledge/Comprehension
13) Movement of the chromosomes during anaphase would be most affected by a drug that
A) reduces cyclin concentrations.
B) increases cyclin concentrations.
C) prevents elongation of microtubules.
D) prevents shortening of microtubules.
E) prevents attachment of the microtubules to the kinetochore.
Answer: D
Type: MC
Topic: Concept 12.2
Skill: Synthesis/Evaluation
14) Measurements of the amount of DNA per nucleus were taken on a large number of cells from
a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In
which stage of the cell cycle did the nucleus contain 6 picograms of DNA?
A) G0
B) G1
C) S
D) G2
E) M
Answer: D
Type: MC
Topic: Concept 12.2
Skill: Application/Analysis
4
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Campbell Biology, Cdn. Ed., 2e (Reece et al.)
Chapter 12 The Cell Cycle
1) The centromere is a region in which
A) chromatids remain attached to one another until anaphase.
B) metaphase chromosomes become aligned at the metaphase plate.
C) chromosomes are grouped during telophase.
D) the nucleus is located prior to mitosis.
E) new spindle microtubules form at either end.
Answer: A
Type: MC
Topic: Concept 12.1
Skill: Knowledge/Comprehension
2) Starting with a fertilized egg (zygote), a series of five cell divisions would produce an early
embryo with how many cells?
A) 4
B) 8
C) 16
D) 32
E) 64
Answer: D
Type: MC
Topic: Concept 12.1
Skill: Application/Analysis
3) If there are 20 chromatids in a cell, how many centromeres are there?
A) 10
B) 20
C) 30
D) 40
E) 80
Answer: A
Type: MC
Topic: Concept 12.1
Skill: Application/Analysis
1
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,11/16/23, 2:42 PM Chapter 12- Midterm 2 (Campbell)
4) For a newly evolving protist, what would be the advantage of using eukaryote-like cell
division rather than prokaryotic binary fission?
A) Binary fission would not allow for the formation of new organisms.
B) Cell division would allow for the orderly and efficient segregation of multiple linear
chromosomes.
C) Cell division would be faster than binary fission.
D) Cell division allows for lower rates of error per chromosome replication.
E) Binary fission would not allow the organism to have complex cells.
Answer: B
Type: MC
Topic: Concept 12.1
Skill: Synthesis/Evaluation
5) Suppose a biologist can separate one of a dozen pieces of chromatin from a eukaryotic
(animal) nucleus. It might consist of which of the following?
A) one-twelfth of the genes of the organism
B) two chromosomes, each with six chromatids
C) a single circular piece of DNA
D) two long strands of DNA plus proteins
E) two chromatids attached together at a centromere
Answer: D
Type: MC
Topic: Concept 12.1
Skill: Knowledge/Comprehension
6) At which phase are centrioles beginning to move apart in animal cells?
A) telophase
B) anaphase
C) prometaphase
D) metaphase
E) prophase
Answer: E
Type: MC
Topic: Concept 12.2
Skill: Knowledge/Comprehension
7) If cells in the process of dividing are subjected to colchicine, a drug that interferes with the
formation of the spindle apparatus, at which stage will mitosis be arrested?
A) anaphase
B) prophase
C) telophase
D) metaphase
E) interphase
Answer: D
Type: MC
Topic: Concept 12.2
Skill: Application/Analysis
2
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,11/16/23, 2:42 PM Chapter 12- Midterm 2 (Campbell)
8) If there are 20 centromeres in a cell at anaphase, how many chromosomes are there in each
daughter cell following cytokinesis?
A) 10
B) 20
C) 30
D) 40
E) 80
Answer: A
Type: MC
Topic: Concept 12.2
Skill: Application/Analysis
9) Where do the microtubules of the spindle originate during mitosis in both plant and animal
cells?
A) centromere
B) centrosome
C) centriole
D) chromatid
E) kinetochore
Answer: B
Type: MC
Topic: Concept 12.2
Skill: Knowledge/Comprehension
10) Taxol is an anticancer drug extracted from the Pacific yew tree. In animal cells, Taxol
disrupts microtubule formation by binding to microtubules and accelerating their assembly from
the protein precursor, tubulin. Surprisingly, this stops mitosis. Specifically, Taxol must affect
A) the formation of the mitotic spindle.
B) anaphase.
C) formation of the centrioles.
D) chromatid assembly.
E) the S phase of the cell cycle.
Answer: A
Type: MC
Topic: Concept 12.2
Skill: Application/Analysis
3
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, 11/16/23, 2:42 PM Chapter 12- Midterm 2 (Campbell)
11) Which of the following are primarily responsible for cytokinesis in plant cells but not in
animal cells?
A) kinetochores
B) Golgi-derived vesicles
C) actin and myosin
D) centrioles and centromeres
E) cyclin-dependent kinases
Answer: B
Type: MC
Topic: Concept 12.2
Skill: Knowledge/Comprehension
12) In which group of eukaryotic organisms does the nuclear envelope remain intact during
mitosis?
A) seedless plants
B) dinoflagellates
C) diatoms
D) dinoflagellates and diatoms only
E) seedless plants, dinoflagellates, and diatoms
Answer: D
Type: MC
Topic: Concept 12.2
Skill: Knowledge/Comprehension
13) Movement of the chromosomes during anaphase would be most affected by a drug that
A) reduces cyclin concentrations.
B) increases cyclin concentrations.
C) prevents elongation of microtubules.
D) prevents shortening of microtubules.
E) prevents attachment of the microtubules to the kinetochore.
Answer: D
Type: MC
Topic: Concept 12.2
Skill: Synthesis/Evaluation
14) Measurements of the amount of DNA per nucleus were taken on a large number of cells from
a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In
which stage of the cell cycle did the nucleus contain 6 picograms of DNA?
A) G0
B) G1
C) S
D) G2
E) M
Answer: D
Type: MC
Topic: Concept 12.2
Skill: Application/Analysis
4
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