Pharmacology Exit HESI Exam Review

Nurse should observe most closely for drug toxicity when a client receives med that has what characteristic Narrow therapeutic index The nurse should observe most closely for drug toxicity when a client receives a medication that has which characteristic? • Low bioavailability • Rapid onset of action • Short half life • Narrow therapeutic index. • Rationale: A drug with a narrow therapeutic index has a high risk for toxicity because there is a narrow range between the therapeutic dose and the toxic dose. Nurse is conducting DC teaching about anti-anxiety drug diazepam (valium) Evaluate the ingredients of all over-the-counter drugs for alcohol content Nursing instruction most important for patient on Zyloprim Increase fluid intake Client getting Tofranil (Imipramine) Give medication at night Magnesium antidote Calcium gluconate Patient with hyperthyroidism taking inderal (propanalol) Decreases pulse rate A client with hyperthyroidism is receiving propranolol (Inderal). Which finding indicates that the medication is having the desired effect? • Decrease in serum T4 levels • Increase in blood pressure • Decrease in pulse rate • Goiter no longer palpable Medication dosing-heparin 25000 units at 7ml/hr doctor changed rate to 900 units what is the Mls/hr Med was ordered 100mg in 4 divided doses in 24 hours available in 25mg, how many will you give every 6 hours 1 Patient on benzos Answer is not narcan - A client experiencing withdrawal from the benzodiazepines alprazolam (Xanax) is demonstrating severe agitation and tremors. What is the best initial nursing action? • Administer naloxone (Narcan) per PNR protocol • Initiate seizure precautions • Obtain a serum drug screen • Instruct the family about withdrawal symptoms. • Rationale: Withdrawal of CNS depressants, such as Xanax, results in rebound over-excitation of the CNS. Since the client exhibiting tremors, the nurse should anticipate seizure activity and protect the client.