Lehne's Pharmacology for Nursing Care
Terms Chapters 1-3
drug - ANSA chemical that can affect the living process
Pharmacology - ANSThe study of drugs and their interactions with living systems
Clinical Pharmacology - ANSThe study of drugs in humans
Therapeutics - ANSAKA "Pharmacotherapeutics"; The use of drugs to diagnose, prevent or treat
disease or to prevent pregnancy
The BIG Three Characteristics any drug can have - ANS1) Effectiveness
2) Safety
3) Selectivity
Effectiveness - ANSEffective Drug= One that elicits responses for which it's given
*Most important property for a drug to have
Safety - ANSSafe Drug= One that can't produce harmful effects even administered in very high
doses for a long time.
*All drugs have the ability to cause injury, especially with high doses and prolonged use
Selectivity - ANSSelective Drug= one that elicits only the response for which it's given
There's no such thing as a wholly selective drug because all drugs cause side effects
Additional Properties of an 'Ideal Drug' - ANS1) Reversible Action
2) Predictability
3) Ease of Administration
4) Freedom from Drug Interactions
5) Low Cost
6) Chemical Stability
7) Possession of Simple Generic Names
Factors that Determine the Intensity of Drug Responses - ANSADMINISTRATION
-Med Errors
- Patient Adherence
PHARMACOKINETICS
, - Absorption
- Distribution
- Metabolism
- Excretion
*SOURCES OF INDIVIDUAL VARIATION
-Physiologic Variables
-Pathologic Variables
-Genetic Variables
PHARMACODYNAMICS
- Drug-receptor interactions
-Patients functional state
-Placebo effect
Pharmacokinetics - ANSThe impact of the BODY on the drugs
Four Processes
1) Drug Absorption
2) Drug Distribution
3) Drug Metabolism
4) Drug Excretion
Pharmacodynamics - ANSThe impact of DRUGS on the body
Examples
- Drug-receptor interactions
- Patients functional state
- Placebo effect
Sources of Variation - ANSPhysiologic Variables
- age, weight, gender
Pathologic Variables
-diminished function in kidney or liver, major organs of elimination
Genetic Variables
Nurses Responsibility Regarding Medications - ANS5 Rights And other rights
5 Rights of Drug Administration - ANS1) Right DRUG
2) Right PATIENT
3) Right DOSE
4) Right ROUTE
5) Right TIME
Terms Chapters 1-3
drug - ANSA chemical that can affect the living process
Pharmacology - ANSThe study of drugs and their interactions with living systems
Clinical Pharmacology - ANSThe study of drugs in humans
Therapeutics - ANSAKA "Pharmacotherapeutics"; The use of drugs to diagnose, prevent or treat
disease or to prevent pregnancy
The BIG Three Characteristics any drug can have - ANS1) Effectiveness
2) Safety
3) Selectivity
Effectiveness - ANSEffective Drug= One that elicits responses for which it's given
*Most important property for a drug to have
Safety - ANSSafe Drug= One that can't produce harmful effects even administered in very high
doses for a long time.
*All drugs have the ability to cause injury, especially with high doses and prolonged use
Selectivity - ANSSelective Drug= one that elicits only the response for which it's given
There's no such thing as a wholly selective drug because all drugs cause side effects
Additional Properties of an 'Ideal Drug' - ANS1) Reversible Action
2) Predictability
3) Ease of Administration
4) Freedom from Drug Interactions
5) Low Cost
6) Chemical Stability
7) Possession of Simple Generic Names
Factors that Determine the Intensity of Drug Responses - ANSADMINISTRATION
-Med Errors
- Patient Adherence
PHARMACOKINETICS
, - Absorption
- Distribution
- Metabolism
- Excretion
*SOURCES OF INDIVIDUAL VARIATION
-Physiologic Variables
-Pathologic Variables
-Genetic Variables
PHARMACODYNAMICS
- Drug-receptor interactions
-Patients functional state
-Placebo effect
Pharmacokinetics - ANSThe impact of the BODY on the drugs
Four Processes
1) Drug Absorption
2) Drug Distribution
3) Drug Metabolism
4) Drug Excretion
Pharmacodynamics - ANSThe impact of DRUGS on the body
Examples
- Drug-receptor interactions
- Patients functional state
- Placebo effect
Sources of Variation - ANSPhysiologic Variables
- age, weight, gender
Pathologic Variables
-diminished function in kidney or liver, major organs of elimination
Genetic Variables
Nurses Responsibility Regarding Medications - ANS5 Rights And other rights
5 Rights of Drug Administration - ANS1) Right DRUG
2) Right PATIENT
3) Right DOSE
4) Right ROUTE
5) Right TIME
