NURS 5334 Adv. Pharmacotherapeutics, Final Review (100% Verified with correct answers)

Why do many medications lack pediatric dosing information in their drug labeling? A. Most medications are not used in pediatric patients. B. There is a lack of evidence-based literature on the safe and effective use of medications in children. C. The FDA does not allow pediatric dosing information in product labeling. D. Only products available as oral liquid formulations are required to contain pediatric dosing information in their labeling. correct answers B. There is a lack of evidence-based literature on the safe and effective use of medications in children. Why are Neonates at greater risk for toxicity with highly protein-bound drugs? A. Protein binding is decreased in neonates increasing the amount of free drug available. B. The protein-bound drugs are not eliminated effectively in neonates. C. Neonates are unable to metabolize these highly protein-bound drugs. D. Protein binding is increased in neonates, making measurement of serum levels of the drug inaccurate. correct answers A. Protein binding is decreased in neonates increasing the amount of free drug available. At what age are adult levels of renal function achieved? • A. 6 months B. 12 months C. 24 months D. 3 years old correct answers B. 12 months What is the list that identifies drugs with a high likelihood of causing adverse effects in the elderly? A. No use list B. Beers list C. Pharmacists list D. Adverse drug list correct answers B. Beers list In pediatric patients gastric acidity does not reach adult values for ______ correct answers 2 Years The principles underlying complication to drug therapy in the elderly include___, ____, ____, and ____. correct answers altered pharmacokinetics, multiple and severe illnesses, multiple-drug therapy, and poor adherence. Altered absorption of drugs in the elderly may result in____drug response correct answers Delay The four major factors that can alter drug distribution in the elderly include _, _, _, and _? correct answers increased body fat, decreased percentage of lean body mass, decreased total body water, and reduced concentration of serum albumin.