Opioids 2023 Practice Questions and Answers 100% Correct

Which of the following agents listed is a phenanthrene opioid that exhibits a full & immediate response to treatment with naloxone in the case of overdose? A. Meperidine B. Fentanyl C. Buprenorphine D. Morphine - ANSWER-D Which of the following statements is correct regarding morphine? A. Morphine is the most lipophilic opioid B. Morphine is metabolized through CYP2D6 and CYP3A4 and has numerous drug interactions C. Morphine has active metabolites that can accumulate in renal impairment, leading to clinically relevant effects D. Morphine can cause opioid-induced constipation upon initiation of opioid therapy, but tolerance occurs after 1-2 weeks of opioid exposure - ANSWER-C A 76-year-old woman presents to the pain clinic with severe pain secondary to a compression fracture in the lumbar spine. Her past medical history is significant for renal insufficiency. She reports that the pain has been uncontrolled with acetaminophen. Which of the following is the best opioid for this patient. A. Morphine (oral) B. Fentanyl (transdermal) C. Meperidine (oral) D. Hydrocodone/acetaminophen (oral) - ANSWER-D A 56-year-old patient has suffered with painful diabetic neuropathy and severe chronic back pain with radiculopathy secondary to spinal stenosis for many years. The patient has failed to receive relief from neuropathic pain with first-line agents, such as TCAs, SNRIs, & anticonvulsants. Which of the following opioids has a dual MOA and should be considered to treat both nociceptive and neuropathic pain in this patient? A. Tapentadol B. Oxymorphone C. Morphine D. Hydrocodone - ANSWER-A Which of the following statements is correct regarding methadone is correct?