Fatty Acid Metabolism MCQ Questions With Complete Solutions

Free fatty acids in the plasma: a) Circulate in the unbound state b) Bind to lipoproteins and circulated c) Bind to albumin and circulated d) Bind to a fatty acid-binding protein and circulated correct answer: c) Bind to albumin and circulated In what compartment does the de novo fatty acid synthesis occur? a) Mitochondria b) Peroxisome c) Endoplasmic reticulum d) Cytosol correct answer: d) Cytosol What is the precursor for fatty acid synthesis? a) Acetyl CoA b) Propionyl CoA c) Succinyl CoA d) Acetoacetyl CoA correct answer: a) Acetyl CoA The conversion of acetyl CoA to malonyl CoA is the rate-limiting step in fatty acid synthesis. Which of the following enzyme catalyzes the above-mentioned reaction? a) Acetyl CoA carboxylase b) Malonyl CoA synthetase c) Acetyl CoA decarboxylase d) Malonyl CoA synthase correct answer: a) Acetyl CoA carboxylase The acetyl CoA is produced in the mitochondria and must be transported into the cytosol for the synthesis of fatty acids. Which of the following is true regarding the transport of Acetyl CoA? a) Acetyl CoA is diffused from the mitochondrial membrane b) Acetyl CoA is transported by its specific transporter protein c) Acetyl CoA is converted into pyruvate, enters into the cytosol and acetyl CoA is regenerated d) Acetyl CoA is converted into citrate, enters into the cytosol and acetyl CoA is regenerated. correct answer: d) Acetyl