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Summary AQA A-level Biology: Gene Expression Revision Notes

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These are full comprehensive notes on the entire Module of Gene Expression for the AQA A-level specification. They are written using a mixture of my own research, class learning and the specification. They include diagrams, step by steps and everything I needed to get an A* in A-level Biology.

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, Gene Expression



Monohrybrid c ro ss e s




Punnett Square used to calculate
probability of offspring genotypes .




eg .
parent genotypes
:
Ff ✗ Ff
F f
F FF Ff
Cross :
f Ff ff




offspring genotypes
:
FF , Ff , Ff , ff



offspring phenotypes :
no CF : CF =3 :/ chance of getting CF :
25%




Autosomal Disorder A disorder caused mutation chromosome that i s not chromosome cystic fibrosis
by genetic on a a s ex
eg .




Sex Linked Disorder If the allele is found on the lower portion of the ✗ chromosome where there i s no
corresponding portion of Y .




eg . red -




green colour blindness , haemophilia Duchenne's ,
muscular Distrophy .




Huntington's Disease




An autosomal dominant disorder . When the allele is expressed , the protein Huntingtin is produced which affects the ner vous system



by breaking down ner vous tissue over many years Patients
. will die around 10-15 years following developing symptoms .




Dominant, Recessive & Codomirart Alleles



dominant I for
9
Only copy of allele needed trait to be expressed in the
phenotype .


eg .

Hurtington s


recessive
only expressed of cystic fibrosis
> allele is in t h e absence dominant allele .


eg .
.




codomirar t 9 Alleles a re expressed equally in the phenotype in a
heterozygous organism Both .
t r a i ts expressed -


eg . colour in




c ows .




Blood Groups .




A B C D red blood

cells

^z
s ^ >

a
°
u
r s
us


Antibodies made in plasma



A B C D


'
un co u
?
no


anti -

B anti -
A antibodies Anti A & Anti B
-
-




0 the universal donor because it doesn't
is has no
antigens so
trigger an immune response .




AB blood can have
any blood donated because t h e re a re no antibodies in t h e blood so no blood type will trigger on immune




response .




1^-1 " 1 BIB IBI IA IB
°
A 1^-10 B AB > 0 9 101°
Genotypes : > or S or codominant recessive

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