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Volledige samenvatting Pathologie Blok 2.4

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Samenvatting Pathologie Blok 2.4
Herhaling zenuwstelsel blok 1.4:
De hypofyse en hypothalamus

Je hebt drie verschillende hormonale regelingen op het
hoogste niveau:
1. Hypothalamus -> Hormoon -> Hormoon
a. Geeft hormonen af die de adenohypofyse
reguleren (Tropinen)
2. Hypothalamus -> Hormoon
a. De hypothalamus is zelf ook een endocrien
orgaan en geeft ADH en oxytocine af d.m.v.
neurohypofyse
3. Zenuw -> Hormoon
a. Bevat centra van het autonome
zenuwstelsel die via sympathische zenuwen
de endocriene cellen van het bijniermerg
stimuleren om hormonen af te geven
(Adrenaline en noradrenaline)

Uitleg regulatie 1:
1. De hypothalamus ontvangt prikkels van neuronen
2. Releasing hormonen (RH) of inhiberende hormonen (IH) worden afgegeven door de
hypothalamus aan de hypofyse
 Releasing is stimulerend, Inhiberend is remmend
3. De hypofyse geeft hormonen af aan een bepaald orgaan (= Doelorgaan)
4. Het endocriene orgaan geeft hormonen af aan de cellen

De hypofyse (Pituitary) bestaat uit de voorkwab en de achterkwab.
Voorkwab (Adenohypofyse)
- Bevat endocriene cellen (Hormonen) en haarvaten
- Gereguleerd, zoals hierboven staat, door de hypothalamus
- Geeft 7 hormonen af (De 1e 4 maken gebruik van negatieve terugkoppeling):
1. Thyroid stimulerend hormoon (TSH)
 Richting de schildklier
 Als reactie op TRH (Thyroid Releasing Hormone)
 Dus: TRH zorgt ervoor dat de hypofyse TSH afgeeft aan de schildklier.
Hierdoor gaat de schildklier schildklierhormonen maken
2. Adrenocorticotroop hormoon (ACTH)
 Richting de bijnier (Voor glucose-stofwisseling)
3. Follikelstimulerend hormoon (FSH)
 Richting de testes en ovaria
4. Luteïniserend hormoon (LH)
 Stimuleer ovulatie
5. Prolactine (PRL)
 Richting de melkklieren
6. Groeihormoon (GH)
 Richting de lever

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Uploaded on
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Number of pages
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Written in
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