MMSC409 Final Exam (100% Errorless Solution)

Identify the organizations and their role in transfusion medicine, including FDA, CBER, AABB, Joint Commission. correct answers 1. FDA = Food and Drug Administration: CFR, CBER, & licensing (a) Code of Federal Regulations (CFR) - blood is a biologic & a drug (b) Center for Biologics Evaluation and Research (CBER) regulates: -blood/component collection -pharmaceuticals manufactured from blood/components (c) Licenses blood collection centers & all aspects (reagents, processes, inspections) 2. AABB: international association of blood centers, transplantation services, individuals (a) Voluntary inspection/accreditation of member institution laboratories (b) Standards to meet CLI'88 and CMS requirements 3. Joint Commission: voluntary inspection/accreditation of member institutions (whole hospital or specific units) Identify/interpret oxygen-hemoglobin dissociation curve and causes for right and left shifts. correct answers Oxyhemoglobin (in % saturation) on y-axis, is plotted against PO₂ (mmHg) on x-axis left shift can be caused by: ↑ - p(CO) & pH (alkalosis) ↓ - temp, DPG, p(CO₂) type of Hgb - fetal right shift can be caused by: ↑ - temp, DPG, p(CO₂) ↓ - p(CO) & pH (acidosis) type of Hgb - adult Determine if a donor would be deferred for results of the "mini-physical." correct answers All of the following requirements must be met: 1. General appearance 2. Weight: require 110 lbs. →autologous donation - if less than 100 lbs., must adjust amount collected/amount of anticoagulant 3. Temperature: 37.5°C (99.5°F) 4. Pulse: 50-100 bpm 5. Blood pressure: -Systolic ≤180 mm Hg -Diastolic ≤100 mm Hg 6. Hemoglobin/hematocrit (Hgb/Hct): -Hgb ≥12.5 g/dL (females) & ≥13.0 g/dL (males) 7. Arm check: for skin lesions & drug abuse