MMSC 420 Exam 3 (A+ Graded Already)

cold reacting antibodies correct answers "LMNOPs" -lewis antibodies: anti-Lea, anti-Leb -anti-M -anti-N -ABO antibodies: anti-A, anti-B, anti-A,B -anti- P1 -anti-S -anti-s anti-M correct answers -usually an IgM antibody, sometimes IgG -enzyme destroyed antigen -displays dosage -cold enhanced -usually not clinically significant: HDFN and HTRs may occur if reacting at 37 C or above -usually naturally occurring or autoantibodies - ~70-80% of people are antigen positive (not many people can form antibody) anti-N correct answers -usually IgM antibody, sometimes IgG -enzyme destroyed antigen -displays dosage -cold enhanced -usually not clinically significant: rare seen antibody, really only seen in renal patients with dialysis (formaldehyde) - ~70-75% of people are antigen positive anti-P1 correct answers -almost always IgM, VERY rare IgG -STRONGLY enzyme enhanced antibody -no dosage -cold enhanced -usually not clinically significant: moderate delayed HTR is possible, HDFN is not possible (IgM) - ~80-95% of people are antigen positive anti-S (big S) correct answers -usually IgG, rare IgM (can be cold reacting) -enzyme destroyed antigen -occasional dosage -cold enhanced if an IgM antibody -usually not clinically significant: rare HTR, HDFN may be severe -only ~30-55% of people are antigen positive anti-s (little s) correct answers -usually IgG, rare IgM (rarely cold reacting) -enzyme destroyed antigen -occasional dosage -cold enhanced if antibody is IgM