MMSC 423 Exam 2 (100% Verified)

Principle of PFA-100 correct answers -Assessment of platelet function -Time required for platelet plug to occlude the aperture is an indication of platelet function Reagent Used in PFA-100 correct answers Citrated whole blood Purpose of PFA-100 correct answers Test platelet function Interpretation of results for PFA-100 correct answers Collagen/EPI → 78-199 seconds Collage/ADP → 55-137 seconds Disease Association with PF-100 correct answers VWD, Bernard-Soulier Glanzmann's Thrombasthenia, Gray Platelet Syndrome (all prolonged) Principle of TEG correct answers Associated with any abnormalities concerning hemostasis 5 parameters: a. R b. K time c. Alpha angle d. MA e. Ly30 Reagent used for TEG correct answers Kaolin → conventional TEG Heparinase → patients on heparin Tissue Factor + Kaolin → rapid TEG Citrated whole blood Purpose of TEG correct answers Measures patient status of coagulopathy Interpretation of results for TEG correct answers Increased R → FFP Increased K → Cryo Decreased alpha angle → Cryo Decreased MA → platelets Increased Ly30 → Transexmic acid, aprotinin Disease association with TEG correct answers Increased R → decreased clot formation Increased K → deficient fibrinogen Decreased alpha angle → deficient fibrinogen Decreased MA → deficient platelets Increased Ly30 → excess fibrinogen PT principle correct answers Time required for formation of a fibrin clot when PPP is added to a thromboplastin-calcium reagent