NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, renal latest 2023 graded A+

NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, renal latest 2023 graded A+ Hematopoiesis blood cell formation Fetus- liver and spleen Adult- bone marrow Anemia A condition in which the blood is deficient in red blood cells, in hemoglobin, or in total volume. Erythropoiesis formation of red blood cells In kidney in response to hypoxia macrocytic normochromic anemia Large RBC's, normal hemoglobin Folic acid or Vitamin B12 deficiency microcytic hypochromic anemia small, abnormally shaped erythrocytes that are not able to carry normal hemoglobin Thalassemia- mediterranean normocytic normochromic anemia Characterized by red cells that are relatively normal in size and normal hemoglobin Aplastic, hemorrhagic, hemolytic, sickle cell iron deficiency anemia anemia resulting when there is not enough iron to build hemoglobin for red blood cells Affects children, poverty, child bearing age Erythrocytes red blood cells Most abundant cell in the body Responsible for tissue oxygenation Mitotic division- 100-120 days sickle cell anemia A genetic disorder in which erythroctyes take on an abnormal curved or "sickle" shape (Hb-s) Thalassemia Inherited defect in the ability to produce hemoglobin, usually seen in persons of Mediterranean background. pernicious anemia Lack of mature erythrocytes caused by inability to absorb vitamin B12 into the bloodstream hemolytic anemia Characterized by an inadequate number of circulating red blood cells due to the premature destruction of red blood cells by the spleen Pancytopenia- reduction in all 3 types of blood cells (RBC, WBC, Plt) Erythropoietin (EPO) Hormone secreted by the kidney to stimulate the production of red blood cells by bone marrow In response to hypoxia In the fetus the liver produces this Hemoglobin Iron-containing protein in red blood cells that carries