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Exam (elaborations)

BCH210 Midterm 2| 316 Questions| With Complete Solutions

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Essential Membrane Functions correct answer: act as barrier regulate import and export of molecules compartmentalization of processes increases efficiency membrane properties correct answer: composed of lipid bilayer impermeable to polar molecules asymmetric membrane fluidity correct answer: lipids and proteins rotate or move within bilayer; allows cell movement, growth, division, secretion, cell junction formation, and self-heal if punctured comformational changes mediate fluid mosaic model correct answer: fluid = components move in membrane mosaic = mix of lipids, proteins, carbs movement differs in pure samples of lipids and in biological membrane asymmetric strucuture of membrane correct answer: two leaflets w dif compositions movement from one leaflet to another is slow (outer to inner) flip flop diffusion correct answer: slow diffusion of polar head group through hydrophobic region glycoproteins and glycolipids correct answer: sugar attached to molecule PTM after protein synthesis important for protein folding and membrane insertion sugar attached by transderase enzyme found on exterior of cells translocase correct answer: enzyme that moves things across membrane maintains asymmetry uses ATP types of lipids (purpose) correct answer: storage, structural, and signalling Lipid physical properties correct answer: hydrophobic (non-polar) and amphiathic (polar & non polar) lipid self-assembly correct answer: aggregate in water to bury hydrophobic groups polar groups interact with water structure formed based on lipid strucutre and interactions (concentration) What lipid would you use to make liposome correct answer: need to form double layer structure phosphatidylethanolamine (PE) has two tails so two leaflets inside out miceles correct answer: non polar region outside polar region in water trapped inside

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BCH210 Midterm 2| 316 Questions|
With Complete Solutions
Essential Membrane Functions correct answer: act as barrier
regulate import and export of molecules
compartmentalization of processes increases efficiency

membrane properties correct answer: composed of lipid bilayer
impermeable to polar molecules
asymmetric

membrane fluidity correct answer: lipids and proteins rotate or
move within bilayer; allows cell movement, growth, division,
secretion, cell junction formation, and self-heal if punctured
comformational changes mediate

fluid mosaic model correct answer: fluid = components move in
membrane
mosaic = mix of lipids, proteins, carbs
movement differs in pure samples of lipids and in biological
membrane

asymmetric strucuture of membrane correct answer: two leaflets
w dif compositions
movement from one leaflet to another is slow (outer to inner)

flip flop diffusion correct answer: slow diffusion of polar head
group through hydrophobic region

,glycoproteins and glycolipids correct answer: sugar attached to
molecule
PTM after protein synthesis
important for protein folding and membrane insertion
sugar attached by transderase enzyme
found on exterior of cells

translocase correct answer: enzyme that moves things across
membrane
maintains asymmetry
uses ATP

types of lipids (purpose) correct answer: storage, structural, and
signalling

Lipid physical properties correct answer: hydrophobic (non-
polar) and amphiathic (polar & non polar)

lipid self-assembly correct answer: aggregate in water to bury
hydrophobic groups
polar groups interact with water
structure formed based on lipid strucutre and interactions
(concentration)

What lipid would you use to make liposome correct answer:
need to form double layer structure
phosphatidylethanolamine (PE)
has two tails so two leaflets

inside out miceles correct answer: non polar region outside
polar region in

,water trapped inside
monolayer

fatty acid chemical structure and charge correct answer: - fatty
part is the carbon chain
- acid part is carboxyl group (-COOH)
- negatively charged

which conformations of saturated fatty acids are most stable?
correct answer: - anti conformation
- extended conformation

unsaturated fatty acids correct answer: double bonds are almost
always in cis conformation which results in kinks in structure

mono-unsaturated fatty acids correct answer: one double bond

octadec-a-noic acid correct answer: saturated fatty acid with all
single bonds

octadec-e-noic acid correct answer: unsaturated fatty acid with
ONE double bond

poly-unsaturated fatty acid correct answer: two or more double
bonds

octadec-adie-noic acid correct answer: unsaturated fatty acid
with TWO double bonds

fatty acid properties/trends correct answer: - more carbons,
higher melting point

, - more double bonds, lower melting point
- number of double bonds has a lower melting point even if it
has more carbons

what non-covalent interaction is involved in packing of fatty
acids? correct answer: van der Waals packing interactions

the storage lipid correct answer: triacylglycerols

where are triacylglycerols primarily found? correct answer:
adipocyte cells (fat cells)

structure of triacylglycerols correct answer: glycerol with three
fatty acid chains

Fatty Acid Nomenclature correct answer: 1) Start from carboxyl
C, then number C's
2) # after ":" is # of double bonds
3) Δ# is where double bonds are
Omega (ω) - start from opposite end

omega fatty acid correct answer: Polyunsaturated fatty acids
that are typically Essential Fatt Acids (EFAs)
obtained from diet
human cannot make

linkages important in triacylglycerols correct answer: ester
linkages

classes of triacylglycerols correct answer: - simple and mixed
(based on fatty acid chains)

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