ONS CHEMO, Top Exam Questions and answers, 100% Accurate. Graded A+

ONS CHEMO, Top Exam Questions and answers, 100% Accurate. Graded A+ Common alkylating agents? The most common alkylating agents known as nitrogen mustards typically include Cyclophosphamide (Cytoxan®) Ifosfamide (Ifex®) Bendamustine (Treanda®). Common platinum-based drugs include Cisplatin (Platinol®) Carboplatin (Paraplatin®). Nitrosoureas Carmustine (BiCNU®) Lomustine (CeeNu®) Streptozocin (Zanosar®) Things to remember w/ Alkylating agents? Cyclophosphamide (and Ifosfamide) can cause Hemorrhagic cystitis (hydration and give Mesna). Oxaliplatin can cause severe Peripheral neuropathy (exacerb. by cold - avoid cold air/drinks). Cisplatin can cause severe nephrotoxicity. Carboplatin can cause severe thrombocytopenia. Nitrosoureas: can cause severe pulmonary/nephro toxicity.