Histology NBME review Exam Questions with 100% Correct Answers

Granulosa cells Correct Answer greatest layer of estrogen secreting cells Predominant component of bone matrix Correct Answer 35% organic (type 1 collagen); 65% inorganic material Contraction of Myoepithelial cells in mammary glands due to what hormone? Correct Answer Acidophilic- Lactoptropes and Mammotropes (prolactin and PRH/PIH prolactin releasing nd inhibiting hormone) GIT- factors in ulcer development Correct Answer Acetylcholine stimulates the release of gastrin produced by enteroendocrine cells of the pyloric antrum which secrete HCL; Histamine (produced by enterochromaffin-like ECL cells) potentiates the effects of Acteylcholine and Gastrin on parietal cells after binding to H2 receptor; Cimetidine is an H2 receptor antagonist that inhibits histamine-depedent acid secretion Contraction of myoepithelial cells Correct Answer oxytocin Site of initial glycosylation Correct Answer N-linked glycosylation (addition of sugars to asparagine begins in the rer and completed in the Golgi); O-linked glycosylation (addition of sugars to serine, threonine, or hydroxylysineby glycosyltransferase in the golgi) Blood cell rich in ige Correct Answer Basophil GIT lymph nodules located Correct Answer Mucosa (MALT) Acrosome Function Correct Answer contains hyaluronidase, which can digest proteoglycan filaments; also has proteolytic enzymes which can digest proteins; allow sperm to enter ovum to fertilize it via these enzymes Apoptosis Activation Correct Answer -Extrinsic (FAS Ligand FAS FADD Procapsases 8/10 Active Capsases Effector Capsases -Intrinsic (growth factor/withdrawal/ DNA damage: X-Ray BCL2 family Effector Capsases) -Severe DNA damage BAX (activation of pro-apoptotic factors) Cytochrome C Mitochondria releases Cytochrome C Apoptosome acted on by Pro-capase-9 and Apaf-1 Capase-9 Pro-capase-3 Capase-3 Apoptosis Drooping of eyelids (myasthenia gravis) Correct Answer Ach receptor in post-synaptic cells is blocked by auto-antibodies