6.3 Viral multiplication
1. Describe the five steps common to the life cycles of all
viruses.
2. Discuss the role of receptors, capsid proteins, and
envelope proteins in the life cycles of viruses.
3. Describe the two most common methods for virion
release from a host cell.
20
,Viral Multiplication
• Mechanism used
depends on viral
structure and genome
• Steps are similar
– attachment to host cell
– entry
– uncoating of genome
– synthesis
– assembly
– release
21
, Attachment (Adsorption)
• Specific receptor attachment
• Receptor determines host preference
– may be specific tissue (tropism)
– may be more than one host
– may be more than one receptor
– may be in lipid rafts providing entry of virus
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1. Describe the five steps common to the life cycles of all
viruses.
2. Discuss the role of receptors, capsid proteins, and
envelope proteins in the life cycles of viruses.
3. Describe the two most common methods for virion
release from a host cell.
20
,Viral Multiplication
• Mechanism used
depends on viral
structure and genome
• Steps are similar
– attachment to host cell
– entry
– uncoating of genome
– synthesis
– assembly
– release
21
, Attachment (Adsorption)
• Specific receptor attachment
• Receptor determines host preference
– may be specific tissue (tropism)
– may be more than one host
– may be more than one receptor
– may be in lipid rafts providing entry of virus
22
