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Questions for STEP 1 - USMLE Forum.

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Biochem: some key enzyme deficiency ones (Lesch Nyhan, Maple Syrup Disease) but all of the questions were very obvious and did not require you to put much thought into it. Don't blow off porphyria and lead poisoning-- for some reason I got so many questions on that! Molecular Bio: This was a big one! lots of questions about DNA regulation, transcription, translation, bacterial plasmids, etc. Sometimes these questions look very scary -- they are always so long and use long names for molecules or restriction enzymes that you have never heard of. You need to get used to the question style and realize that what they are asking is very simple. The NBME forms have questions very similar to the molecular bio ones I saw on the exam. Pharm: Another one I thought would be difficult but not. Big drugs you should know a lot about (like antihypertensives, drugs for hyperlipidemias, cardic drugs, etc.) know side effects -- especially the chemo and immunosupressant drugs that kept on tripping me up so much. Micro/Immuno: mostly bacterial processes and what you would use to treat them... or what was their mechanism of disease (i.e. endotoxn, exotoxin, etc.) Know immunology and cytokines well, as well as the functions of all the cells. Different immune deficiencies were all asked on my exam (there is one page in First Aid that sums them up very well). Anatomy/Neuroanatomy: Always combined with a pathology question or an imagine. I had a few branchial plexus/lumbar plexus questions. Many questions would give you a clinical scenario, then ask you to identiy the artery/nerve/organ on a CT scan/MRI/angiogram/brain cross section. Physio: This was almost always combined with Pathology--they would ask the physiology behind some path process. I had so many questions where the question asked "what would be the levels of x, y, and z enzymes/hormones?", answer choices being "increased, decreased, etc" Pathology: lot of images -- MANY more than Qbank's representation.

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