Cso Exam Prep 2023 With Complete Solutions.

CSO EXAM PREP 2023 WITH COMPLETE SOLUTIONS. A cancer patient is unable to provide self-care. His disease is progressing rapidly and prognosis is poor. Which number likely represents his Karnofsky Performance Status? A. 100 B. 70 C. 40 D. 0 - ANSWER C. 40 Disabled; requires special care & assistance. ************************************************** 0 - DEAD 100 - no evidence of disease A cancer patient is fully active and able to carry on all pre-disease activities without restrictions. Which Eastern Cooperative Oncology Group (ECOG) grade is appropriate? A. Grade 0 B. Grade 1 C. Grade 2 D. Grade 3 - ANSWER A. Grade 0 is fully active and able to carry on all pre-disease activities without restrictions. (KS 90-100) For Cancer Prevention: The American Institute for Cancer Research (AICR) recommends that Americans stay physically active for at least ______minutes every day - ANSWER For Cancer Prevention: The American Institute for Cancer Research (AICR) recommends that Americans are physically active for at least 30 minutes every day. Limit sedentary behavior like watching TV. If the pyloric valve (located at the base of the stomach) was removed or manipulated during surgery, the patient is at risk for _______________________________ - ANSWER DUMPING SYNDROME If the pyloric valve (located at the base of the stomach) was removed or manipulated during surgery, the patient is at risk for DUMPING SYNDROME True or False A patient with a new ileostomy should avoid both soluble and insoluble fiber after surgery - ANSWER TRUE Patients should avoid SOLUBLE fiber until the surgeon confirms the intestine has healed. Nestle Health Science suggests limiting MCT oil to _____mL/day - ANSWER Nestle Health Science suggests limiting MCT oil to 100 mL/day (~6.5 TBSP) =760 kcals True or False The ketogenic diet limits carbohydrate intake to 5-10% of the total diet, typically between 15-50 grams daily - ANSWER True The ketogenic diet limits carbohydrate intake to 5-10% of the total diet, typically between 15-50 grams daily Generally, the Macrobiotic diet is made up of these foods: - ANSWER The Macrobiotic diet is made up of: •organic whole grains (50% of food intake) •locally grown, organic fruits/vegs (25% of diet) •soups made with vegetables, seaweed, beans, fermented soy (miso) (up to 25% food intake) Generally, the Macrobiotic diet does NOT include A. Dairy, eggs, poultry, red meat B. Artificial flavors, processed foods or chemical additives C. Mango, pineapple and papaya D. Both A & B E. Answers A, B & C - ANSWER Answer: E Zoledronic acid (Zometa®) is a supportive care drug in the category of bisphosphonates that can be used to decrease complications produced by metastasis to the: A. Brain B. Bone C. Liver D. Kidney - ANSWER Zoledronic acid (Zometa®) is a supportive care drug in the category of bisphosphonates to decrease complications produced by metastasis to the: B. BONE Which dietary supplements should be recommended when a patient is prescribed Zoledronic acid for stage IV breast cancer with bone metastasis? - ANSWER Co-administer oral calcium 500 mg and a multiple vitamin containing 400 IU Vit D daily. Reference: St. John's Wort may ______________________ the drug activity of Vinblastine (Velban) & Vincristine (Oncovin) - ANSWER DECREASE St. John's Wort may DECREASE the drug activity of Vinblastine (Velban) & Vincristine (Oncovin) by INDUCING Cytochrome P450 3A4 (CYP3A4). CYP3A4 is an important enzyme in the body, mainly found in the liver and in the intestine. It oxidizes xenobiotics, such as toxins or drugs, so that they can be removed from the body. TRUE or FALSE Grapefruit juice (GFJ) can INCREASE a drugs' activity by INHIBITING the enzyme responsible for the drug's metabolism - ANSWER TRUE Example: Concomitant use of GFJ and docetaxel resulted in a reduction of clearance greater than 15% Name 3-4 foods that can alter the CYP3A4 metabolizing enzyme- thus altering a drugs' efficacy/toxicity - ANSWER Possible food & drug interactions occur with: •grapefruit and GFJ ••pomegranate •star fruit *citrus juice/ seville oranges (In the USA, Seville oranges are grown on a limited scale by small farmers) There are many different herbal supplements that affect CYP3A enzymes, including these 5 supplements: - ANSWER •St John's Wort •Black cohosh •Ginseng •Ginko biloba •Goldenseal Which chemotherapy drug is known to cause Pharyngolaryngeal dysesthesia? - ANSWER Oxaliplatin (Eloxatin).