Molecular Diagnostics - Week 1: Introduction to Molecular Diagnostics questions with correct answers

Molecular Diagnostics - Answer Combination of laboratory medicine, molecular genetics and technology Molecular Diagnostics in Health Care - Answer Techniques allow detection of pathogenic mutations in nucleic acids to facilitate detection, diagnosis, classification, prognosis and therapy monitoring Clinical Applications of Molecular Diagnostics - Cancer - Answer Used in diagnosis, classification, stage determination and tumor analyses. Example conditions include B/T cell lymphomas, CML, Ewings sarcoma and Rhabdomyosarcoma Clinical Applications of Molecular Diagnostics - Inherited Diseases - Answer May be used in their diagnosis, treatment and management. Examples include Fragile X syndrome, Leiden Factor V and hereditary hemochromatosis Clinical Applications of Molecular Diagnostics - Infectious Diseases - Answer Molecular techniques may be used to monitor treatment, determine viral loads, drug sensitivity and to perform genotyping. Can apply to viruses (e.g. Epstein-Barr Virus, Cytomegalovirus, Human Immunodeficiency Virus) and bacteria (e.g. Mycobacterium tuberculosis, Neisseria gonorrhoeae, Chlamydia trachomatis) as well as fungi, protozoa etc. Peripheral Blood - Answer White Blood Cells are required as red blood cells do not contain nuclei. Typically 50 ul is sufficient for most molecular testing