NU 636 CASE STUDY POLYPHARMACY | NU 636-7C: Advanced Pharmacology
NU 636 CASE STUDY POLYPHARMACY | NU 636-7C: Advanced Pharmacology. Also, digoxin a cardiac glycoside that inhibits Na-K ATPase and causes parasympathetic stimulation of the autonomic nervous system in managing heart failure and atrial fibrillation can be associated with dizziness and mental disturbances (Rehman & Hai, 2021). Piroxicam is a nonsteroidal anti-inflammatory that Inhibits the synthesis of prostaglandins in body tissues thus reduces pain. Sadly, the use of NSAIDs such as piroxicam leads to cardiac decompensation in the elderly with existing heart failure (Bleumink et al., 2003). Furthermore, paracetamol, Mylanta, and coloxyl are common over-the-counter medications. While paracetamol is used for mild pain by blocking peripherally pain impulses, it's associated with hepatic toxicity which can cause disorientation. Mylanta (Aluminum/Magnesium hydroxide) and coloxyl (docusate sodium) are oral antacid suspensions use for heartburn /indigestion, and constipation respectively. While the use of Mylanta is associated with constipation and diarrhea. Likewise, the use of docusate sodium as a stool softener in patients with CHF such as Mrs. A. should be done with caution due to its sodium content. Pharmacokinetic Changes in the Geriatric Population that May Affect Drug Disposition Pharmacokinetics examines the absorption, distribution, metabolism, and excretion of...................
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