Exam (elaborations) NURS 660

What is the medication that is the antidote for alprazolam? - ANSWER flumazenil What is the MOA of pregabalin that makes it alleviate pain for people with fibromyalgia or chronic fatigue? - ANSWER binds to the alpha 2 delta sub-units of voltage sensitive calcium channels What is an antagonist of caffeine - ANSWER adenosine Diagnose this pt: Patient comes in with a CC of anxiety. She has been excessively worrying, increased arousal, increased tiredness and irritability. What is the primary and least likely diagnosis? - ANSWER GAD; Panic Disorder Somebody w/ anxiety worries about having a panic attack, in addition has mood changes to avoid things in order to not have a panic attack. - ANSWER Panic disorder A woman was raped, and continues to have fear of opposite sex on her way to parking garage. Which two areas of the brain are involved? - ANSWER amygdala and hippocampus MOA of modafinil (Provigil). How does it promote normal wakefulness - ANSWER histamine, NE at alpha adrenergic receptor sites, dopamine at D2 receptors What is the MOA of eszopiclone? What receptors does it act on? - ANSWER Binds to GABA receptors to increase GABA to increase sleepiness Which would be the first line appropriate pharmacological agent for PTSD? - ANSWER Paroxetine What mediation is used to alleviate to help cognitive pain and physical symptoms in fibromyalgia? - ANSWER Milnacepran (Savella) With the difficulty breathing is related hypothetically to the activation of what area of the brain? - ANSWER parabrachial nucleous What medications are good for falling asleep "sleep induction" and are not addictive? - ANSWER Suvorexant (Belsmora) Know the MOA of buspirone. Which receptor does it primarily act upon? - ANSWER serotonin 1a 5HT1A partial agonist