BCPS 2023 Exam Questions With Complete Solutions

BCPS 2023 Exam Questions With Complete Solutions anti htn of choice in pregnancy - ANSWER methyldopa, labetolol AC of choice in pregnancy - ANSWER enox n/v meds for pregnancy - ANSWER pyridoxine, doxylamine, meclizine, dimenhydrainate avoid in breastfeeding - ANSWER opioids, contrast (x3wks after), buproprion/varenicline combined hormonal contraception post partum - ANSWER 3 weeks if no risk factors, 6 weeks if risk factor early breakthrough bleeding vs late breakthrough - ANSWER increase estrogen vs increase progestin (after at least 3 month trial) significant reduction in birth control efficacy know from - ANSWER rifampin, anticonvulsants, lamotrigine (it is decreased by OC) antibiotics and OC - use backup method with . . . - ANSWER don't have to have an alternate unless pt uncomfort or has breakthrough bleeding standard estrogen component in combined oral contraceptives - ANSWER 20-34 mcg progestone only pills - missed pill if taken how late? - ANSWER 3 hours infertility at 35, 35 - ANSWER 35 = 1 year of trying; 35 = 6 mo treatment of HSV - initial infection - ANSWER acclovir 400 mg PO TID x 7-10 d (only treats symptoms; virus doesn't go away) suppressive therapy for HSV infection - - ANSWER acyclovir 400 mg PO BID or valacyclovir 500 mg po daily gonococcal infection treamtnet - ANSWER treat for chlamydia too; ceftriax 250 mg IM x 1 plus azithro pelvic inflammatory disease - ANSWER cefotetan 2 g IV q12h or cefoxitin 2 g iv q6h + doy - treat until clinical improvement bacterial vaginosis - treatments - ANSWER metronidazole or clindamycin calculation for Risk ratio - ANSWER RR = A/(A+B) / C/(C+D) Calculation for odds ratio - ANSWER OR = A/C / B/D analysis used for discreet data - ANSWER chi squared type of analysis used for continuous data - ANSWER t-test, two sample if data is split into two groups common tests for heterogenity in meta-analyses - ANSWER x2 or cochrane Q calculate number needed to treat - ANSWER 1/absolute risk reduction (only calculate if stastically significant difference found) osmolality of plasma, CNS fluid - ANSWER 270-300 mOsm/kg; 280-300 mOsm/kg max osmo of peripheral injections for no pain - ANSWER 900 injection pain and buring FD&C Act of 1938 - required proof of ? - ANSWER safety (thalimide) Defauver-harris amendment of 1962 required proof of? - ANSWER efficacy Generic drug pathway act was? - ANSWER Hatch-Waxman Act - Drug price competition and patent term restoration acto f 1984 Durham-humphrey amendment of 1951 did what - ANSWER established difference between Rx and non-rx SSRIs with greatest 2D6 inhibition - ANSWER fluoxetine, paroxetine (very high) SSRIs with greatest 1A2 inhibition - ANSWER fluvoxamine (high), fluoxemine (med) first line antidepressants - ANSWER SSRI, SNRI, mirtaz, bupro - NOT TCA bc of suicide potential (success) SSRI with longest half life - ANSWER fluoxetine activating SSRIs - ANSWER sertraline, fluoxetine sedating SSRIs - ANSWER paroxetine, fluvoxamine