Ati Pharmacology Rn Science All Solution 100% Correct Answers Spring Fall-2023/24 Edition Guaranteed Grade A+

Digoxin (lanoxin) SE blurred/double vision Guaifenesin SE can cause drowsiness Estrogen (premarin) SE ↑ risk of Thromboembolism with s/s: SOB, severe headache, vomiting, sudden acute pain in the calves, legs, chest, abdomen. Doxepin (Sinequan) [anticholinergic] SE urinary retension, constipation, drying of nasal/oral secretons, ↑HR Albuterol (Proventil) [sympathomimetic/ adrenergic beta-2 agonist] Contraindicated with MAOIs (can↑ action of albuterol and → HTN crisis); β-blockers can inhibit the therapeutic effects Use: invert canister, shake before use, rinse mouth after use, w/new inhaler perform test spray Levothryoxine (T4) Indication hypothyroidism RT dysfxn of hypothalamus, pituitary, or thyroid gland Cephalosporins (Keflex) allergy to cephalosporins is considered a precaution for taking penicillins Phenobarbital [Barbiturates]; interventions for anticonvulsant therapy assess for resp. depression, excess sedation from toxic effects, IV at 50mg/min, avoid extravasation (alkaline→skin damage) Sumatriptan (Imitrex) use when migraine symptoms appear and again in 1 hr if symptoms persist Route—fastest/most effective intravenous Narcan [opioid antagonist] therapeutic action: improvement of respiratory rate Baclofen (Lioresal) Therapeutic action ↓ frequency & severity of muscle spasms Erythromycin (Erythrocin) [macrolide] SE liver toxicity What do need to avoid when taking Spironolactone (Aldactone) [K sparing diuretic] foods w/ ↑ K such as salt substitutes Chloroquine phosphate (Aralen): Indication malaria prevention; Use: take weekly starting 1 week before departure and continued for 4 weeks after return. Heparin (anticoagulant) Use w/alteplase for acute MI Warfarin (Coumadin) Use long-term prophylaxis of thrombosis [antidote—Vit K] Clopidogrel (Plavix) Use reduce long-term risk of clotting w/ atherosclerosis and recent MI of CVA Alteplase (Activase) [antithrombolytic] Use Acute MI/CVA (has short half-life) Methylphenidate (Concerta) Use marcolepsy Precaution: avoid caffeine use Testosterone IM use If use to correct delayed puberty→assess bone maturation with bi-annual x-rays of hand and wrist; monitor liver function (can ↑ hypoglycemia, potentiate sleep apnea, exacerbate heart failure due to fluid retention. Diphenoxylate & Atropine (Lomotil) Caution With Renal impairment ↓ elimination of atropine → ↑ anticholinergic effects of atropine like confusion Loperamide (Imodium) use anti-diarrheal (poorly absorbed from GI tract; difficulty crossing the blood-brain barrier) Methylcellulose (Citrucel) use bulk-forming agent with minimal Side Effects (SE) Psyllium (Metamucil) use bulk-forming agent with minimal Side Effects (SE) Acetazolamide (Diamox) [diuretic] indication edema, epilepsy, acute mountain sickness, glaucoma (↓ intraocular pressure by ↓ amount of aqueous humor in the eye) Contra: allergy to sulfonamides Metoprolol (Lopressor) [β-blocker] use and side effects Hold dose for dyspnea (sign of exacerbation of CHF) Propanolol (Inderal) Use. Dysrhythmia, HTN, angina; SE: bronchoconstriction/bronchospasm; can block glyconeogenesis Norgestrel (Ovrette) use and contraindication contraception; SE: excess progestin →weight gain from ↑ appetite; deficiency of progestin: late breakthrough bleeding, amenorrhea; excess estrogen → edema Medroxyprogesterone (Provera); Contra: smoking/tobacco products; Risks: Thromboembolism & Cardiovascular complications; Interventions: use additional contraceptive measures w/antibiotic therapy IM injection site locate dorsogluteal site Nausea tx antiemetic plus cool, damp cloth to forehead, neck, and wrists. Allopurinol (Zyloprim) indication Gout; MofA: ↓ serum uric acid levels & urinary uric acid secretion; Precaution: avoid foods that acidify urine such as corn TB—multi drug tx Isoniazid(INH), Rifampin, pyrazinamide, ethambutol—to deal w/ resistant strains ACE Inhib. Lisinopril (Zestril) SE dry/persistent cough for 1-2 wks from ↑ bradykinin Furosemide (Lasix) [loop diuretic] Intervention check BP before giving to determine baseline; can cause ↓ BP by ↓ circulatory volume or by relaxing venous smooth muscle Ticlopidine (Ticlid) indication prevent coronary artery thombosis; Intervention: check platelet count What intervention needs to be preformed before giving an IV medications assess site for redness/swelling before administration Collagenase (Santy) use Debride ulcers Interferon Use Prevent viral replication Isotretinoin (Accutane) contraindication pregnancy w/ 2 forms of birth control due to teratogenic effects Epoetin Alfa (Procrit) indication treat anemia; SE: headache, HTN, seizures RT Hct rises too quickly Urofollitropin (Fertinex) side effect ovarian hyperstimulation syndrome. Hypertensive crisis S/S flushed skin, headache, visual changes Acetylcysteine (Mucomyst) indication prevent liver damage following acetaminophen (Tylenol) overdose. Most effective if given shortly after ingestion; some protection up to 24 hrs. Montelukast (Singulair) indication prevent asthma exacerbations;Dose: daily at bedtime; SE: well tolerated CONTINUED..