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The common marmoset genome provides insight into primate biology and evolution

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2022/2023 Written for academic year
Institution Portage Learning
Course Marmoset genome
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Here we report the whole-genome sequencing and assembly of the genome of the marmoset, the first New World monkey to be sequenced (Supplementary Note). Our results include comparisons of this platyrrhine genome with the available catarrhine (human, other hominoid and Old World monkey) genomes, identifying previously undetected aspects of catarrhine genome evolution, including positive selection in specific genes and significant conservation of previously unidentified segments of noncoding DNA. The marmoset genome displays a number of unique features, such as rapid changes in microRNAs (miRNAs) expressed in placenta and nonsynonymous changes in protein-coding genes involved in reproductive physiology, which might be related to the frequent twinning and/or chimerism observed.

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