Biochemistry Unit 2 Explained! Practice Questions

Which of the following statements about the different levels of protein structure is true? ANSWERS: The interactions between the side chains of the amino acids make up the tertiary level structure of a protein Which type of bonding or interaction is correctly paired with a chemical or change in environment that will disrupt/break the interaction or bond? ANSWERS: Hydrogen bonds/ionic bonds: Change in pH Which of the following statements about protein structure and stability is true? ANSWERS: Which of the following statements about protein structure and stability is true? The negatively charged amino acid, Glutamate, is replaced with the negatively charged amino acid Aspartate. Which level of protein structure is most significantly impacted by this change? ANSWERS: Primary structure Which of the following pairs of amino acids are NOT likely to interact with one another to stabilize tertiary structure? ANSWERS: Option 4 Primary structure consists of the order of in a protein. These are held together with bonds that are formed by a reaction. ANSWERS: Amino acids, peptide, dehydration As a piece of bacon is heated in a skillet on the stove, you observe that the appearance of the bacon changes. You may even notice that the bacon becomes crispy if left in the skillet. What types of bonds or interactions in proteins are susceptible to temperature changes? ANSWERS: Hydrophobic interactions If lysine is required at position #150 in the peptide chain in order for a protein to properly fold and function, what happens if amino acid #150 is mutated from lysine to leucine? ANSWERS: The protein will not fold properly Glutamine at position 16 forms an important interaction with Serine in a different location in the protein. How would the protein structure be affected if the Glutamine in position 16 were mutated to Leucine? Would this increase or decrease the stability of the protein? ANSWERS: Increase. Leucine and Serine form a stronger ionic bond together