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AGNP Board Exam – Men’s Health Prescription(Questions And Answers)

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AGNP Board Exam – Men’s Health Prescription(Questions And Answers) Question: Levofloxacin (Levaquin), used to treat acute bacterial prostatitis, is a: fluoroquinolone. Correct penicillin. macrolide. tetracycline. Explanation: Levofloxacin (Levaquin) is classified as a fluoroquinolone. An example of a penicillin is amoxicillin (Moxatag); macrolide is azithromycin (Zithromax); and a tetracycline is doxycycline (Doryx). Question: Ciprofloxacin, used for the treatment of bacterial prostatitis, is a potent CYP1A2 inhibitor and is absolutely contraindicated with other CYP1A2 inhibitors. An example of another CYP1A2 inhibitor is: ketoconazole. tizanidine (Zanaflex). Correct fluoxetine hydrochloride (Sarafem). celecoxib (Celebrex). Explanation: Ciprofloxacin, a fluoroquinolone, is a strong CYP1A2 inhibitor and is absolutely contraindicated for concomitant administration of tizanidine (Zanaflex). Concomitant use may increase the serum concentration of tizanidine. If use with another strong inhibitor cannot be avoided, initiate tizanidine at an adult dose of 2 mg and increase in 2-4 mg increments based on response. Ketoconazole is a CYP3A4 inhibitor; celecoxib is a CYP2D6 inhibitor; and fluoxetine is a YP2C19 inhibitor. CYP1A2 inhibitors are enzymes that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Question: A 33-year-old man has been taking sulfamethoxazole/trimethoprim for the treatment of bacterial prostatitis. Brand names of this medication do NOT include: Azulfidine. Correct Bactrim DS. SMX-TMP DS. Sulfatrim


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