AGNP Board Exam – Neurology Assessment Exam 3(Questions And Answers)

AGNP Board Exam – Neurology Assessment Exam 3(Questions And Answers) 1. Question: Which of the following medications is NOT a serotonin 5-HT1 receptor agonist? Axert. Fioricet. Correct Maxalt. Zomig. Explanation: Fioricet is a combination of butalbital, acetaminophen and caffeine. Axert (almotriptan), Maxalt (rizatriptan), Zomig (zolmitriptan) are all classified as serotonin 5-HT1 receptor agonists, or triptans. 2. Question: A patient presenting with a transient ischemic attack (TIA) is taking nifedipine (Adalat CC) for hypertension. Pharmacokinetics of nifedipine may be altered in patients with: renal insufficiency. hepatic impairment. Correct irritable bowel disease. G6PD deficiency. Explanation: Since hepatic biotransformation is the predominant route for the disposition of nifedipine, the pharmacokinetics may be altered in patients with chronic liver disease. Patients with hepatic impairment have a longer disposition half-life and higher bioavailability of nifedipine than healthy volunteers. 3. Question: Oxcarbazepine (Trileptal) is structurally similar to: carbamazepine (Tegretol). Correct divalproex sodium (Depakote). lamotrigine (Lamictal). topiramate (Topamax). Explanation: As the name suggests, oxcarbazepine (Trileptal) is related to carbamazepine (Tegretol, Carbatrol) and appears to be similarly effective for controlling complex partial seizures and primary and secondary generalized tonic-clonic seizures. It seems to cause fewer unwanted side effects in many (but not all) patients. Oxcarbazepine is not effective against absence or myoclonic seizures.