NBCE Part 1 - Microbiology –Review- 182 QUESTIONS- WITH COMPLETE SOLUTIONS

Type 1 hypersensitivity is ________________. CORRECT ANSWERS: anaphylactic (immediate) **ie. bronchial asthma, bee sting, hay fever -- allergies** What antibody & cells are associated w/ Type 1 Hypersensitivity? CORRECT ANSWERS: IgE, mast cells, basophils Mast cells makes ________________. CORRECT ANSWERS: histamine Type 2 hypersensitivity is ________________. CORRECT ANSWERS: cytotoxic **ie. Goodpasteur's Syndrome (lungs & kidney) & erythroblastosis fetalis (Coombs anemia)** What is erythroblastosis fetalis? CORRECT ANSWERS: occurs when the father & baby are Rh+ & the mom is Rh- What antibody & cells are associated w/ Type 2 hypersensitivity? CORRECT ANSWERS: IgG -- targets cells for phagocytosis **2 THINGS FOR TYPE 2: antigen + antibody** Typer 3 hypersensitivity is ________________. CORRECT ANSWERS: immune-complex mediated **ie. Lupus, RA, Arthus rxn (local necrosis), serum sickness (systemic)** What antibody is involved in Type 3 hypersensitivity? CORRECT ANSWERS: IgG & complement **3 THINGS FOR TYPE 3: antigen + antibody + complement** Type 4 Hypersensitivity is ________________. CORRECT ANSWERS: delayed -- aka cell mediated or cellular **ie. TB, transplat rejection via MHC** What cells are involved in Type 4 hypersensitivity? CORRECT ANSWERS: T-Cell lymphocytes **ONLY hypersensitivity rxn that is NOT antibody mediated** Eukaryotes have a ____________ & _____________