NUR 641E Midterm Exam Study Guide 2023 Graded A+

NUR 641E Midterm Exam Study Guide 2023 Graded A+ Prodrug - ANSWER-An inactive drug dosage form that is converted to an active metabolite by various biochemical reactions once it is inside the body. -Cytochrome P450 -Ex. Aspirin, psilocybin, heroin Bioavailability - ANSWER-the rate at and the extent to which a nutrient is absorbed and used -Affected by route of administration and drug dosage -Drug clearance (rate drug leaves circulation) -Steady state concentration -Affected by chemical stability, solubility, and first pass Steady state (of a drug) - ANSWER-stable level of drug in the body, occurs in 5 half lives of the drug -rate of drug being added to system is equal to amount being eliminated from system Pharmacokinetics - ANSWER-The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. -what the body does to the drug