NURS 615 Pharm Exam 4 Review.

NURS 615 Pharm Exam 4 Review. Week Twelve 1. What is tiotropium used to treat? (Spiriva) Tiotropium bromide (INN) is a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is used for maintenance treatment of chronic obstructive pulmonary disease (COPD) which includes chronic bronchitis and emphysema. It is not however used for acute exacerbations. Tiotropium is a muscarinic receptor antagonist, often referred to as an antimuscarinic or anticholinergic agent. Although it does not display selectivity for specific muscarinic receptors, when topically applied it acts mainly on M3 muscarinic receptors[8] located on smooth muscle cells and submucosal glands. This leads to a reduction in smooth muscle contraction and mucus secretion and thus produces a bronchodilatory effect. 2. What are the adverse effects with montelukast (Singular)? Side effects of Singulair can include skin rash, mood changes, tremors, headache, stomach pain, heartburn, upset stomach, nausea, diarrhea, tooth pain, tiredness, fever, stuffy nose, sore throat, cough, and hoarseness. Singulair may interact with phenobarbital or rifampin 3. What patient teaching should accompany the prescription of montelukast (Singulair)? Singulair will not work fast enough to treat an asthma attack that has already begun. Use only a fast-acting inhalation medicine to treat an asthma attack. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing attacks. Call your doctor right away if you feel that this medicine is not working as well as usual, or if it makes your condition worse. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor.