AS Level Biology B (Advancing Biology) H022/01 Foundations of biology

Friday 20 May 2022 – Afternoon AS Level Biology B (Advancing Biology) H022/01 Foundations of biology Time allowed: 1 hour 30 minutes INSTRUCTIONS • Use black ink. You can use an HB pencil, but only for graphs and diagrams. • Write your answer to each question in the space provided. If you need extra space use the lined pages at the end of this booklet. The question numbers must be clearly shown. • Answer all the questions. • Where appropriate, your answer should be supported with working. Marks might be given for using a correct method, even if your answer is wrong. INFORMATION • The total mark for this paper is 70. • The marks for each question are shown in brackets [ ]. • This document has 24 pages. ADVICE • Read each question carefully before you start your answer. Turn over SECTION A You should spend a maximum of 25 minutes on this section. Write your answer for each question in the box provided. Answer all the questions. 1 Which option is a short-term effect of a pollutant on the respiratory system? A Asthma attack B Chronic bronchitis C Emphysema D Lung cancer Your answer [1] 2 Herceptin is a drug used in immunotherapy to treat breast cancer. Which of the statements about treating cancer with Herceptin is correct? A Chemicals bind to oestrogen to prevent transcription in cancer cells. B Ionising radiation binds to cancer cells. C Specialised antibodies are attracted to cancer cells. D Toxic chemicals destroy cancer cells. Your answer [1] 3 Which of the statements about a false-negative screening test for breast cancer is correct? A A follow-up biopsy confirms that no cancer is present in the breast tissue. B A mammogram looks abnormal even though no cancer is present. C A mammogram looks normal even though cancer is present. D The person looking at the mammograms records a positive result by mistake. Your answer [1]