AMNH genetic and genomic in nursing Exam with correct Answers

Why do genetic counseling programs include extensive courses on laboratory methods in genetics - ANSWER To help patients understand testing procedures and results What is the heritability estimate for schizophrenia in the general populations - ANSWER 80% Caucasian take more warfarin than asia - ANSWER Many Asian do not breath down warfarin as fast as caucasians, so the drug is more effective at lower dosages What type of genetic test process information about as a symptomatic person's risk for having a child with a specific autosomal recessive disorder in the future - ANSWER Carrier test What variable in a person with CAD increase the likelihood of a strong influence in its expression - ANSWER the problems is severe before age 50 An adult daughter whose mother gas bipolar disease because she engages in all of the following behaviors. Which behavior should be explored further as a manifestation of bipolar disease - ANSWER Making frequent purchases of expensive clothing that she never wears A woman whose sister tested + for a specific mutation in the BRCA1 gene, which increases the risk of breath and ovarian cancer, is found not th have mutation but does have a mutation of unknown significance near the known mutation site. How should this woman be counseled? - ANSWER She should be informed that she does not have the specific mutation but that because another mutation is present she should be vigilant about screening. What should be told to the pt who have been found to have genetic mutation that increase the risk of colon cancer and says he does not want any of his family to know about their result - ANSWER It is not required that you tell anyone about this Renault, However because your sibling and children may also be at risk for common cancer, you should think about how this information might help them Why is pharmacokinetics of particular interest in treating pt with psychiatric health problems - ANSWER Psychiatric meds may be effective in only a small group of Pts. A pt with a very high concentration of insulin receptors on cells that require insulin for glucose to enter. How should insulin dosages be adjusted for this patient to have blood glucose levels with the normal range - ANSWER Insulin dosages should be decreased because the drug will exert its action at lower concentrations Why are general physician and surgeons NOT considered to be genetics professionals - ANSWER The focus on their professional education is the study of Medicine rather than genetics Which type of body tissue have the highest risk for cancer development - ANSWER Any tissue that retains the ability to divide Under which condition would genetic testing for predisposition to an inherited disorder in a miner be considered reasonable - ANSWER When the risk is high and prophylaxis to reduce disorder severity is available. Which statement about cancer is true - ANSWER Cancer cells arise from normal cells Which type of genetic testing is the more sensitive method for detecting any mutation in a specific gene - ANSWER Direct DNA sequencing Which normal cell characteristic is represented by the production of insulin in the beta cells of the pancreas - ANSWER Performance of a differentiated function How do genetic issues influence individual variation of the response to a specific drug - ANSWER Polymorphism of genes encoding metabolizing enzymes Which condition suggests attention ADHD - ANSWER 9 yr old does not focuse on a favorite story for longer than 3 min Gene-to-gene interaction in which that action of one gene modified the expression of a different gene - ANSWER Epistasis Pt states that the origin of most cancer is genetic. What is the best response - ANSWER Cancers arise in cells that have alteration in the genes Woman as 3 aunts with breast cancer. Which genetic professional would be most appropriate for assistance in helping her understand the health risk - ANSWER Genetic counsler Fact about schizophrenia - ANSWER Copy number variants appear to play the most important role in genetic risk for schizophrenia In which body or cell area are most genes in the humans located - ANSWER Nucleus Best description of the genetic contribution to onset of autism - ANSWER Known causes of autism spectrum include copy number variants and chromosomal problems Heritability estimate for addiction to alcohol in bot males and females - ANSWER 50-60% Which action reflects promoting of genomic care as part of comprehension health care - ANSWER Ensuring that genomic issues potentially influencing a person health are incorporated into routing care Lethal cardiac arrhythmia with long QT - ANSWER Torsade de Pointes How do genetic counselors provide emetic information to pts and families in a no directive manner - ANSWER Presenting all facts and available options in a manner that neither promotes nor excludes any legally permitted decision or action What is the most accurate classification of the common forms of CAD and HTN - ANSWER Complex disorders resulting from gene environment interactions Juliet tells a nurse that she has 3 aunts who were diagnosed with great cancer. She asks if she should have genetic testing. - ANSWER Your family history may indicate an increased risk for breath cancer and a genetic counselor could help determine whether you could benefit from genetic testing An 85 yr old pt stress that she does not perform breast self-exam because there is not history of breast cancer in her family. What is the best response. - ANSWER Breast cancer can be found more frequently in some families however the risk for general non-familiar breast cancer increases with age. Your pt Maggie insist that her mother have genetic testing to determine if her breast cancer is connected to a mutation in the BRCA1/2 genes. Maggie is concerned about her own risk for getting breast cancer and that of her children, but Maggie's mom does not want to be tested. What ethical principle is on of several that must be considered in evaluation this case - ANSWER Maggie's mother right to pricaxy How are malignant rumors different from benign tumors - ANSWER Benign tumors have totally normal features, and malignant tumors have totally abnormal features Which condition provided the greatest support for a strong genetic contribution to autism spectrum disorder - ANSWER Concordance among dizygotic twins is 10 % What statement regarding behavioral genetic is accurate - ANSWER A genetic predisposition toward a specific behavior can be modified by altering environment influence What is the result of mutation occurring in a suppressor gene - ANSWER Loss of an existing function What would be the expected response to a skin injury if the involved tissue has lost the normal cell characteristic of contact inhibition - ANSWER Excessive growth fof replacement tissue Pts response to normal drug dose that because of a genetic variation in an enzyme that prepares the drug for elimination results in a blood drug level that is below the minimum effective concentration - ANSWER The intended response fails to be produced Which statement AFib is true - ANSWER A variety of different genes contribute to its expession what is the genetic contributing to the development of the most common forms of atherosclerosis - ANSWER Variation in a verity of genes each exertion a small effect A pt with fox elbow in ER states that he named MS for pain rather than codiene because the last time he had a painful injury codeine was not effective in managing he's pain. What is the nurse's best response - ANSWER Communicate this information to the admitting physician What is the relationship among genes, DNA and proteins - ANSWER A gene is a section of DNA that provided the directions for synthesizing a specific protein For pt who have familial hypercholestrolemia,what should be the focus of teaching for